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N-(4-Nitrobenzoyl)glycine

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Identification
Molecular formula
C9H8N2O5
CAS number
19541-61-0
IUPAC name
2-[(4-nitrobenzoyl)amino]acetic acid
State
State

The compound is present as a solid at room temperature. Its crystalline nature is indicative of its organized internal structure, and it is primarily used in laboratory environments for chemical syntheses and research purposes.

Melting point (Celsius)
167.00
Melting point (Kelvin)
440.15
Boiling point (Celsius)
371.00
Boiling point (Kelvin)
644.15
General information
Molecular weight
210.17g/mol
Molar mass
210.1550g/mol
Density
1.5230g/cm3
Appearence

N-(4-Nitrobenzoyl)glycine typically appears as a yellow crystalline powder, often used in research and various chemical syntheses. Its solid form is distinct due to its bright yellow color, which is attributed to the nitro group present in the compound's structure.

Comment on solubility

Solubility of 2-[(4-nitrobenzoyl)amino]acetic acid

The solubility of 2-[(4-nitrobenzoyl)amino]acetic acid exhibits interesting characteristics due to its unique chemical structure. This compound, with a functional group profile that includes both amino and carboxylic acids, suggests a moderate potential for solubility in polar solvents.

Several factors contribute to its solubility behavior:

  • Polarity: The presence of polar functional groups may enhance its ability to interact with water molecules, likely facilitating dissolution.
  • Hydrogen Bonding: The carboxylic acid group can form hydrogen bonds with the solvent, which often increases solubility.
  • Substituents: The 4-nitro substituent can influence electron distribution within the molecule, potentially affecting solvation dynamics.

It is essential to note that the exact solubility may vary with conditions such as temperature and pH. As with many organic compounds, it may exhibit enhanced solubility in organic solvents compared to aqueous environments. This dual solubility profile provides a unique challenge and opportunity for researchers handling this compound.

In summary, while precise solubility data may vary, 2-[(4-nitrobenzoyl)amino]acetic acid is expected to be soluble in various polar solvents due to its structural features.

Interesting facts

Interesting Facts about 2-[(4-nitrobenzoyl)amino]acetic acid

2-[(4-nitrobenzoyl)amino]acetic acid, commonly known in scientific circles for its significant biochemical relevance, is a compound that stands out due to its unique functional groups and applications. Here are some notable points about this intriguing compound:

  • Biochemical Roles: This compound features an amine group, which plays a crucial role in protein synthesis. The presence of the nitro group enhances its reactivity, making it a valuable tool in medicinal chemistry.
  • Potential Therapeutic Applications: Due to its structure, 2-[(4-nitrobenzoyl)amino]acetic acid is investigated for its potential to act against various diseases, including cancer. The nitro group has shown promise in increasing the potency of certain drug formulations.
  • Reaction Mechanism: Understanding its reaction mechanisms provides insights into how it can be manipulated in synthetic chemistry, including the development of novel pharmaceutical compounds.
  • Research Significance: This compound is often studied in the context of pharmacology and organic synthesis, making it a subject of interest for students and researchers alike who are looking to explore innovative applications.
  • Application in Drug Design: The ability of 2-[(4-nitrobenzoyl)amino]acetic acid to serve as a precursor or intermediate in complex drug designs makes it particularly valuable in the field of drug discovery.

In summary, 2-[(4-nitrobenzoyl)amino]acetic acid is not merely a compound with a complex structure; it represents a convergence of chemistry and medicine. As researchers continue to probe its properties, the potential for this compound to contribute to scientific advancements remains promising. It is a testament to how compounds, through their unique characteristics, can pave the way for groundbreaking discoveries in health and disease management.

Synonyms
4-Nitrohippuric acid
2645-07-0
2-(4-Nitrobenzamido)acetic acid
4-Nitrobenzoylglycine
p-Nitrobenzoylglycine
2-[(4-nitrobenzoyl)amino]acetic acid
CCRIS 6077
EINECS 220-156-5
UNII-9HIU46T98M
NSC 33334
BRN 1125394
9HIU46T98M
DTXSID8025759
NSC-33334
4-09-00-01199 (Beilstein Handbook Reference)
NITROHIPPURIC ACID, P-
DTXCID005759
(4-NITROBENZOYLAMINO)ACETIC ACID
2-((4-NITROBENZOYL)AMINO)ACETIC ACID
para-nitrohippuric acid
220-156-5
N-(4-Nitrobenzoyl)glycine
Glycine, N-(4-nitrobenzoyl)-
P-NITROHIPPURIC ACID
Hippuric acid, p-nitro-
N-(p-Nitrobenzoyl)glycine
Glycine, N-(p-nitrobenzoyl)-
CHEMBL8682
N-4-Nitrobenzoylglycine
[(4-nitrobenzoyl)amino]acetic acid
p-Nitrohippursaure
MFCD00007349
Oprea1_067067
Oprea1_078681
SCHEMBL1285585
2-(4-Nitrobenzamido)aceticacid
(4-Nitro-benzoylamino)-acetic acid
ALBB-025756
NSC33334
Tox21_201181
BDBM50016603
AKOS000200803
AKOS015889410
FN71140
HY-W028991
SB79883
SDCCGMLS-0065545.P001
2-[(4-nitrophenyl)formamido]acetic acid
NCGC00091799-01
NCGC00091799-02
NCGC00258733-01
PD119724
CAS-2645-07-0
DB-046957
CS-0073015
NS00028117
EN300-23706
D97784
SR-01000009743
SR-01000009743-1
Q27272566
Z56936638
F0873-0006