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2-(4-nitrophenyl)aniline

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Identification
Molecular formula
C12H10N2O2
CAS number
3645-68-9
IUPAC name
2-(4-nitrophenyl)aniline
State
State

At room temperature, 2-(4-nitrophenyl)aniline is typically found in a solid state. The compound is noted for its stability under standard conditions but should be handled with care to prevent degradation or reaction with other chemicals.

Melting point (Celsius)
162.50
Melting point (Kelvin)
435.60
Boiling point (Celsius)
398.40
Boiling point (Kelvin)
671.50
General information
Molecular weight
214.22g/mol
Molar mass
214.2130g/mol
Density
1.3250g/cm3
Appearence

2-(4-nitrophenyl)aniline appears as a yellow to orange solid. It is an organic compound that may exhibit crystal-like properties depending on its purity and processing. It can also manifest as a powder in some preparations.

Comment on solubility

Solubility of 2-(4-nitrophenyl)aniline

The solubility of 2-(4-nitrophenyl)aniline, also known as p-nitroaniline derivative, presents an interesting profile due to its molecular structure and functional groups. This compound exhibits varying solubility in different solvents:

  • Water: Generally, 2-(4-nitrophenyl)aniline is considered insoluble in water due to the hydrophobic nature of its aromatic rings.
  • Organic solvents: It shows better solubility in organic solvents such as ethanol, acetone, and chloroform, which can effectively solubilize non-polar or weakly polar compounds.

This solubility behavior underscores the compound's aromatic structure and the presence of the nitro group, which impacts its polarity. As quoted from materials science literature, "the solubility of compounds can profoundly affect their reactivity and biological activity." Thus, understanding the solubility characteristics of 2-(4-nitrophenyl)aniline is crucial for its applications in various chemical processes and formulations.

Interesting facts

Interesting Facts about 2-(4-nitrophenyl)aniline

2-(4-nitrophenyl)aniline, commonly known in the field of organic chemistry, is a fascinating compound with a variety of properties and applications. Here are some intriguing facts that showcase its significance:

  • Structure and Activity: The compound consists of an aniline group attached to a nitrophenyl moiety. The presence of the nitro group is responsible for its enhanced reactivity and has important implications in dye chemistry.
  • Applications: This compound is primarily used in the dye industry. It serves as a precursor for various azo dyes, which are used extensively in textiles, inks, and plastics.
  • Pharmaceutical Relevance: Due to its structural characteristics, 2-(4-nitrophenyl)aniline has shown potential in medicinal chemistry, particularly in the development of new pharmaceuticals that target specific biological pathways.
  • Environmental Concerns: Similar to other nitro compounds, the environmental impact of 2-(4-nitrophenyl)aniline is a topic of study, as nitro group derivatives can contribute to pollution if not handled properly.
  • Research Significance: Ongoing research into this compound often focuses on its electronic properties and how they influence chemical reactivity, making it of great interest in both academic and industrial settings.

In summary, 2-(4-nitrophenyl)aniline is much more than just a simple organic compound. Its unique structure affords it valuable properties that make it essential in various fields, particularly in dye manufacturing and pharmaceutical development. As researchers continue to explore its capabilities, the implications of this compound are sure to expand.

Synonyms
6272-52-2
4'-Nitro-biphenyl-2-ylamine
4'-Nitro-[1,1'-biphenyl]-2-amine
2-(4-nitrophenyl)aniline
4'-Nitro-2-biphenylamine
2-BIPHENYLAMINE, 4'-NITRO-
MLS002639355
4'-nitro[1,1'-biphenyl]-2-amine
NSC-30863
4'-Nitro-(1,1'-biphenyl)-2-amine
2-Amino-4'-nitrobiphenyl
EINECS 228-462-0
NSC 30863
BRN 2806990
[1,1'-Biphenyl]-2-amine, 4'-nitro-
NSC30863
MFCD01740422
4-nitrophenyl benzenamine
4'-Nitro-2-aminobiphenyl
A6SQ344JTL
4-12-00-03236 (Beilstein Handbook Reference)
CHEMBL352290
SCHEMBL3010864
DTXSID30211804
HMS3091E13
[2-(4-nitrophenyl)-phenyl]-amine
AKOS024260529
AB09889
SMR001548800
DB-073179
CS-0341627
NS00035148