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4-Nitrophenethyl alcohol

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Identification
Molecular formula
C8H9NO3
CAS number
100-27-6
IUPAC name
2-(4-nitrophenyl)ethanol
State
State

At room temperature, 4-Nitrophenethyl alcohol is found in a solid state. It appears as crystalline solids or a powder, depending on its specific form and purity.

Melting point (Celsius)
75.00
Melting point (Kelvin)
348.15
Boiling point (Celsius)
303.00
Boiling point (Kelvin)
576.15
General information
Molecular weight
167.16g/mol
Molar mass
167.1640g/mol
Density
1.2910g/cm3
Appearence

4-Nitrophenethyl alcohol is typically found as a colorless or pale yellow crystalline solid. It may also be encountered as crystals or a crystalline powder, which is characteristic of many small organic molecules.

Comment on solubility

Solubility of 2-(4-nitrophenyl)ethanol

2-(4-nitrophenyl)ethanol, with the chemical formula C8H9NO3, exhibits interesting solubility properties. Specifically, this compound is known to be:

  • Soluble in organic solvents: It demonstrates good solubility in common organic solvents such as ethanol, methanol, and acetone, allowing it to be easily utilized in various organic reactions.
  • Partially soluble in water: Due to the presence of the hydroxyl group (-OH) which can form hydrogen bonds with water, 2-(4-nitrophenyl)ethanol possesses some degree of polarity. However, the overall hydrophobic character of the aromatic ring limits its solubility in aqueous solutions.
  • Dependence on temperature: The solubility can increase with rising temperatures, a common trait in many organic compounds, enabling improved dissolution under elevated conditions.

In summary, while 2-(4-nitrophenyl)ethanol is not highly soluble in water, its solubility in organic solvents makes it valuable for applications in organic synthesis and chemical reactions. As a general rule, "Like dissolves like," and the combination of hydrophobic and hydrophilic characteristics in this compound exemplifies this principle.

Interesting facts

Interesting Facts about 2-(4-nitrophenyl)ethanol

2-(4-nitrophenyl)ethanol is a fascinating compound that draws interest from both chemists and biochemists alike. This compound, also known for its role as a key intermediate in various synthetic pathways, showcases a unique set of characteristics that make it essential in multiple fields of study.

Key Highlights:

  • Structural Significance: The presence of both an alcohol (-OH) and a nitro group (-NO2) in its structure allows for **diverse reactivity**, making it a versatile building block in organic synthesis.
  • Biological Role: This compound has been studied for its **potential pharmaceutical properties**, with research indicating possible applications in medicinal chemistry, particularly as an antiseptic agent.
  • Environmental Impact: The **nitro group** makes 2-(4-nitrophenyl)ethanol an important subject of environmental studies, as nitro compounds can undergo transformation leading to aromatic amines, which are known for their toxicity.

Notably, 2-(4-nitrophenyl)ethanol has caught the attention of scientists examining the role of nitro compounds in biological systems. As one researcher aptly stated, “Understanding the impact of such compounds may illuminate pathways to novel therapeutics.” This highlights the compound’s significance in ongoing studies aimed at discovering new treatment modalities.

In summary, 2-(4-nitrophenyl)ethanol exemplifies not only the intricacies of organic compounds but also the **interconnectivity of chemistry**, **biology**, and **environmental sciences**, making it an intriguing subject for further research and exploration.

Synonyms
4-Nitrophenethyl alcohol
100-27-6
2-(4-Nitrophenyl)ethanol
4-Nitrobenzeneethanol
Benzeneethanol, 4-nitro-
P-NITROPHENETHYL ALCOHOL
2-(p-Nitrophenyl)ethanol
2-(4-nitrophenyl)ethan-1-ol
Phenethyl alcohol, p-nitro-
4-Nitro-benzeneethanol
CCRIS 6079
EINECS 202-835-8
MFCD00010202
NSC 55519
BRN 1866148
DTXSID7025764
AI3-36320
DTXCID305764
4-06-00-03083 (Beilstein Handbook Reference)
2-(4-nitro-phenyl)-ethanol
AKOS 90322
4-nitrobenzene-ethanol
4-Nitrophenethylalcohol
4-NITROPHENETHANOL
2-(p-nitrophenyl) ethanol
2-(4-nitrophenyl)-ethanol
Oprea1_314753
SCHEMBL250473
4-Nitrophenethyl alcohol, 99%
CHEMBL1485974
2-(4-Nitrophenyl)ethyl Alcohol
P-NITROPHENYLETHYL ALCOHOL
BCP04523
CS-M0671
NSC55519
Tox21_200285
CK2458
NSC-55519
AKOS000279533
AKOS015967331
FN31119
PS-4048
NCGC00091653-01
NCGC00091653-02
NCGC00091653-03
NCGC00257839-01
CAS-100-27-6
SY059047
1-(2-HYDROXYETHYL)-4-NITROBENZENE
DB-019472
N0569
NS00022963
EN300-141955
Z276600186
202-835-8