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Not a common trivial name

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Identification
Molecular formula
C23H19NO4S
CAS number
438056-69-0
IUPAC name
2-(4-phenylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
State
State

At room temperature, this compound is a solid. Its solid state is important for its stability and ease of handling in various applications.

Melting point (Celsius)
222.00
Melting point (Kelvin)
495.15
Boiling point (Celsius)
485.00
Boiling point (Kelvin)
758.15
General information
Molecular weight
423.50g/mol
Molar mass
423.5030g/mol
Density
1.3450g/cm3
Appearence

The compound is a solid material that often appears as a crystalline powder. It may be seen as white or off-white, demonstrating its purity and composition.

Comment on solubility

Solubility of 2-(4-phenylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxylic acid

The solubility of 2-(4-phenylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxylic acid (C23H19NO4S) is influenced by several factors, including its molecular structure and the presence of functional groups. This compound features both sulfonyl and carboxylic acid functionalities, which can significantly impact its solubility in various solvents.

Solubility Characteristics:

  • Polar Solvents: It is likely to exhibit better solubility in polar solvents due to the presence of the –COOH group, which can engage in hydrogen bonding.
  • Non-Polar Solvents: The overall hydrophobic nature introduced by the phenyl groups might limit solubility in non-polar solvents.
  • Aqueous Solubility: Expected to have limited water solubility unless conditions such as pH are optimized to enhance the ionization of the carboxylic acid.

In general, while solubility can vary widely with temperature and specific solvent interactions, the structural features of this compound suggest a moderate solubility profile, particularly in organic solvents and moderately polar environments. Further experimental data would be invaluable to determine specific solubility parameters and aid in practical applications.

Interesting facts

Interesting Facts about 2-(4-phenylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxylic acid

This intriguing compound belongs to the class of isoquinoline derivatives, which have attracted attention in medicinal chemistry due to their diverse biological activities. Here are some fascinating insights about this compound:

  • Structure & Stability: The unique structure of this compound features a sulfonyl group, which plays a critical role in enhancing solubility and stability. The presence of the phenyl groups contributes to the aromatic character, which can influence the electronic properties of the molecule.
  • Biological Significance: Isoquinoline derivatives are known for their potential therapeutic effects. This compound may serve as a lead structure in drug discovery, as isoquinolines have shown promise in treating a range of conditions, including cancer and neurodegenerative diseases.
  • Synthetic Routes: The synthesis of such complex compounds often involves multi-step reactions, which can challenge chemists. Understanding these synthetic pathways is crucial for developing efficient and eco-friendly methods in medicinal chemistry.
  • Research Applications: This compound, like other isoquinolines, is an exciting target for ongoing research. Scientists are exploring its potential as an anti-inflammatory agent, among other therapeutic applications.
  • Diversity of Derivatives: The chemical diversity within the isoquinoline family means that modifications to the structure can lead to significantly different biological activities, emphasizing the importance of structure-activity relationships (SAR) in drug development.

As we explore the world of chemical compounds, 2-(4-phenylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxylic acid serves as a compelling example of how intricate molecular design can lead to potential advancements in medicine and chemistry.

Synonyms
(R)-2-([1,1'-Biphenyl]-4-ylsulfonyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid
SCHEMBL4308168
191326-92-8
2-(4-phenylphenyl)sulfonyl-3,4-dihydro-1H-isoquinoline-3-carboxylic acid
PD041922