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2-(4-Pyridyl)-1,3-benzoxazole

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Identification
Molecular formula
C12H8N2O
CAS number
4217-32-1
IUPAC name
2-(4-pyridyl)-1,3-benzoxazole
State
State

At room temperature, 2-(4-Pyridyl)-1,3-benzoxazole is solid. This stability in solid form allows for its use in various applications, including as an intermediate in organic synthesis and in research environments.

Melting point (Celsius)
130.00
Melting point (Kelvin)
403.00
Boiling point (Celsius)
410.00
Boiling point (Kelvin)
683.00
General information
Molecular weight
196.21g/mol
Molar mass
196.2050g/mol
Density
1.3150g/cm3
Appearence

2-(4-Pyridyl)-1,3-benzoxazole typically appears as a crystalline solid with a color that can range from off-white to light brown. Its crystalline nature can be noted under a microscope, where small, often prism-like structures are observable. It is widely used in chemical research and applications due to this stable solid form.

Comment on solubility

Solubility of 2-(4-pyridyl)-1,3-benzoxazole

2-(4-pyridyl)-1,3-benzoxazole exhibits fascinating solubility characteristics. This organic compound is known for its **moderate polarity**, which influences its interaction with various solvents. Here are some key points regarding its solubility:

  • Solvent Compatibility: It typically dissolves well in polar solvents like dimethyl sulfoxide (DMSO) and methanol, while showing limited solubility in non-polar solvents.
  • Hydrogen Bonding: The presence of nitrogen in the pyridine ring allows for potential hydrogen bonding, enhancing solubility in polar environments.
  • pH Influence: Solubility can also be affected by the pH of the solution, as protonation of the nitrogen atom can alter the compound's characteristics.
  • Temperature Dependence: As with many organic compounds, solubility generally increases with temperature, making higher temperatures favorable for dissolution.

In summary, the solubility of 2-(4-pyridyl)-1,3-benzoxazole is significantly influenced by solvent choice, pH, and temperature. Understanding these factors is essential for its applications in various chemical processes.

Interesting facts

Interesting Facts about 2-(4-Pyridyl)-1,3-benzoxazole

2-(4-Pyridyl)-1,3-benzoxazole, a fascinating heterocyclic compound, has attracted significant attention in the field of medicinal chemistry. This compound is notable for its multifaceted properties and potential applications:

  • Biological Activity: 2-(4-Pyridyl)-1,3-benzoxazole exhibits promising antibacterial and antifungal activities. Its unique structure allows it to interact with various biological targets, making it a candidate for drug development.
  • Fluorescent Properties: One of the intriguing aspects of this compound is its fluorescence. These properties can be exploited in bioimaging and analytical techniques, allowing scientists to visualize cellular processes in real-time.
  • Binding Affinity: The presence of the pyridine ring enhances the compound's ability to form hydrogen bonds, which can lead to higher binding affinity with biological receptors. This trait is essential in the design of inhibitors for various enzymes.
  • Synthetic Routes: The synthesis of 2-(4-Pyridyl)-1,3-benzoxazole involves several methods, allowing chemists to explore alternative pathways. This flexibility is valuable for optimizing yield and purity during the production process.
  • Research Interest: Ongoing research focuses on modifying this compound to improve its efficacy and reduce potential side effects. The structure-activity relationship is an essential area of study, providing insights into how variations in the compound's structure affect its biological activity.

Overall, 2-(4-Pyridyl)-1,3-benzoxazole serves as a noteworthy example of how organic compounds can be harnessed for innovative applications in pharmaceuticals and beyond. Its rich chemistry promises exciting developments in future research endeavors and therapeutic applications.

Synonyms
BENZOXAZOLE, 2-(4-PYRIDYL)-
2-pyridin-4-yl-1,3-benzoxazole
2295-47-8
2-(4-Pyridyl)benzoxazole
R.754
2-(pyridin-4-yl)-1,3-benzoxazole
BRN 0610289
2-(pyridin-4-yl)benzoxazole
2-(4-pyridinyl)benzoxazole
4-(Benzoxazol-2-yl)pyridine
SCHEMBL4544648
CHEMBL2269947
DTXSID70177495
NSTYHODPDRPTRO-UHFFFAOYSA-N
2-(4-pyridinyl)-1,3-benzoxazole
STL196748
AKOS015953294
AH-357/03403049