Skip to main content

4-Pyridylacetic acid

ADVERTISEMENT
Identification
Molecular formula
C7H7NO2
CAS number
614-13-1
IUPAC name
2-(4-pyridyl)acetic acid
State
State

At room temperature, 4-Pyridylacetic acid is typically found in a solid state. It remains stable under normal conditions, showing little hygroscopic behavior.

Melting point (Celsius)
115.00
Melting point (Kelvin)
388.00
Boiling point (Celsius)
307.00
Boiling point (Kelvin)
580.00
General information
Molecular weight
137.14g/mol
Molar mass
137.1410g/mol
Density
1.1870g/cm3
Appearence

4-Pyridylacetic acid is a solid compound that can appear as colorless or white crystalline powder. Its distinct feature is the carboxylic acid group attached to a pyridine ring at the para position, which contributes to its crystalline nature. The purity and physical characteristics might slightly vary based on the sample and its processing.

Comment on solubility

Solubility of 2-(4-pyridyl)acetic acid

2-(4-pyridyl)acetic acid, known for its unique structure involving a pyridine ring, exhibits notable solubility characteristics that are of interest in various chemical applications.

Solubility in Water

This compound is moderately soluble in water, mainly due to the presence of the carboxylic acid group which can hydrogen bond with water molecules. Factors affecting its solubility include:

  • The ionic nature of the carboxyl group enhances interactions with polar solvents.
  • The size and sterics of the pyridine ring may partially impede complete dissolution.

Solubility in Organic Solvents

In terms of organic solvents, 2-(4-pyridyl)acetic acid displays good solubility in:

  • Ethanol
  • DMSO (Dimethyl sulfoxide)
  • Acetone

This solubility in various solvents highlights its versatility and potential for use in organic synthesis and pharmaceutical applications.

Factors Influencing Solubility

Several key factors can influence the solubility of 2-(4-pyridyl)acetic acid, including:

  • Temperature: Increasing temperature typically increases solubility.
  • pH Levels: In acidic conditions, the acid remains protonated, possibly affecting its solubility.

Overall, the solubility profile of 2-(4-pyridyl)acetic acid makes it an important compound for researchers to consider in their work, particularly when selecting the right solvent for reactions or formulations.

Interesting facts

Interesting Facts about 2-(4-pyridyl)acetic Acid

2-(4-pyridyl)acetic acid is a fascinating compound that falls within the category of pyridine derivatives. As a chemical scientist or a chemistry student, here are some intriguing aspects to consider:

  • Structure and Functionality: The compound contains both a pyridine ring and a carboxylic acid functional group, which contributes to its diverse chemical reactivity and potential applications in various chemical reactions.
  • Biological Significance: Many pyridine derivatives, including 2-(4-pyridyl)acetic acid, exhibit biological activity. This compound has been studied for its potential as a biosynthetic precursor in the pharmaceutical industry, particularly in the development of medications that target neurological conditions.
  • Interaction with Metal Ions: 2-(4-pyridyl)acetic acid has the ability to chelate metal ions, forming stable complexes. This property is important in the fields of catalysis and material science.
  • Research Applications: In the realm of research, this compound is often utilized in studies related to organic synthesis, medicinal chemistry, and material science, showcasing its versatility in experimental settings.

Additionally, the compound's unique structure allows it to participate in hydrogen bonding, further influencing its behavior in different environments. One intriguing quote from chemists in the field often emphasizes that "the chemistry of pyridine derivatives offers a plethora of opportunities in drug design and synthesis."

With ongoing research and exploration, 2-(4-pyridyl)acetic acid continues to reveal its potential, making it a noteworthy subject of study for chemists and researchers alike.

Synonyms
4-Pyridineacetic acid
28356-58-3
2-(pyridin-4-yl)acetic acid
4-Pyridylacetic acid
(4-pyridinyl)acetic acid
4-carboxymethylpyridine
EINECS 248-990-5
SN2796229G
DTXSID1067382
UNII-SN2796229G
RefChem:100441
DTXCID5037810
248-990-5
pyridine-4-acetic acid
2-pyridin-4-ylacetic acid
2-(4-pyridyl)acetic acid
MFCD03701446
pyridin-4-yl-acetic acid
Pyridin-4-ylacetic acid
4-pyridin-acetic acid
4-pyridyl-acetic acid
4-pyridine acetic acid
4-pyridine-acetic acid
2-(pyridin-4-yl)aceticacid
SCHEMBL48554
SCHEMBL7968621
SCHEMBL8040203
CHEMBL1801805
4-pyridineacetic acid, AldrichCPR
SBB005759
AKOS005216598
AC-6580
B22P919
AS-38253
ST097547
SY258148
CS-0046227
NS00014747
F040098
SR-01000944882
SR-01000944882-1