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2-(4-pyridyl)quinoline-4-carboxylic acid

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Identification
Molecular formula
C16H10N2O2
CAS number
143603-77-8
IUPAC name
2-(4-pyridyl)quinoline-4-carboxylic acid
State
State

At room temperature, 2-(4-pyridyl)quinoline-4-carboxylic acid exists as a solid.

Melting point (Celsius)
310.00
Melting point (Kelvin)
583.10
Boiling point (Celsius)
614.10
Boiling point (Kelvin)
887.30
General information
Molecular weight
262.27g/mol
Molar mass
262.2790g/mol
Density
1.3110g/cm3
Appearence

2-(4-pyridyl)quinoline-4-carboxylic acid typically appears as a crystalline solid.

Comment on solubility

Solubility of 2-(4-pyridyl)quinoline-4-carboxylic acid

The solubility of 2-(4-pyridyl)quinoline-4-carboxylic acid can be characterized by several key factors:

  • Solvent Polarity: This compound exhibits greater solubility in polar solvents due to its ability to form hydrogen bonds and engage in dipole-dipole interactions. Common solvents include water, ethanol, and methanol.
  • pH Dependence: The solubility is also influenced by the pH of the solution. At lower pH values, the carboxylic acid group can remain protonated, potentially limiting solubility. Conversely, at higher pH, deprotonation can enhance solubility.
  • Temperature Effects: Generally, as with many organic compounds, increasing the temperature can improve solubility. Experimentation may reveal specific temperature thresholds that optimize dissolution.

Furthermore, it is noteworthy to mention that co-solvents can play a significant role in dissolving this compound effectively, creating a more favorable interaction with the molecular structure. As a result, chemical scientists often need to analyze the solubility in various solvent mixtures to achieve ideal conditions.

In summary, the solubility of 2-(4-pyridyl)quinoline-4-carboxylic acid is a variable element influenced by solvent choice, pH, and temperature, highlighting the need for careful consideration in experimental design and application.

Interesting facts

Interesting Facts about 2-(4-pyridyl)quinoline-4-carboxylic acid

2-(4-pyridyl)quinoline-4-carboxylic acid, often affectionately referred to as a "multi-functional molecule," is notable for its versatile applications in various fields of science. Here are some fascinating insights about this compound:

  • Pharmaceutical Relevance: This compound has attracted attention due to its potential role in medicinal chemistry, where it may serve as a precursor for various drugs, particularly in treating diseases related to the central nervous system.
  • Chelating Agent: Its ability to coordinate with metal ions makes it a powerful chelating agent, which can be exploited in environmental chemistry and various analytical techniques.
  • Fluorescent Properties: 2-(4-pyridyl)quinoline-4-carboxylic acid exhibits fluorescence, making it useful for applications in luminescent materials and as a dye in biological imaging.
  • Synthetic Pathways: The synthetic routes to obtain this compound can involve various techniques, including reactions involving quinoline derivatives and carboxylic acid formations, showcasing the creativity of organic chemistry.
  • Pyridine Influence: The presence of the pyridine ring contributes significantly to the compound's chemical reactivity and biological activity, leading to interesting studies in heterocyclic chemistry.

Furthermore, the synthesis of 2-(4-pyridyl)quinoline-4-carboxylic acid opens avenues for researchers to explore new derivatives and analogs, promoting the discovery of innovative therapeutic agents. As one enthusiastic chemist put it, "The beauty of organic synthesis lies in its endless possibilities.”

Overall, this compound's diverse characteristics make it a topic of interest for both academic research and industrial applications, exemplifying the intersection of chemistry, biology, and materials science.

Synonyms
2-(pyridin-4-yl)quinoline-4-carboxylic acid
673-274-8
14228-23-0
2-(4-pyridinyl)-4-quinolinecarboxylic acid
2-pyridin-4-ylquinoline-4-carboxylic acid
2-Pyridin-4-yl-quinoline-4-carboxylic acid
4-Quinolinecarboxylic acid, 2-(4-pyridinyl)-
MFCD00687610
NSC360211
2-(4-pyridyl)quinoline-4-carboxylic acid
CINCHONINIC ACID, 2-(4-PYRIDYL)-
NSC-360211
CHEMBL415737
2-(4-Pyridyl)cinchoninic acid
NSC 360211
2-(4-Pyridyl)cinchoninsaeure [German]
BRN 0017972
2-(4-Pyridyl)cinchoninsaeure
Kyselin 2-(4-pyridyl)-cinchoninova [Czech]
Kyselin 2-(4-pyridyl)-cinchoninova
8U2ZPK2XZA
Cambridge id 5542580
NCIStruc1_000902
NCIStruc2_000832
Oprea1_338008
Oprea1_758729
5-25-05-00236 (Beilstein Handbook Reference)
SCHEMBL116042
SCHEMBL29788465
DTXSID90161997
IBXRRNLSWGROLA-UHFFFAOYSA-N
ALBB-000774
AR3149
BBL009856
BDBM50097097
CCG-37557
NCGC00014819
NCI360211
SBB011934
STK364547
AKOS000121700
AB06957
NCGC00014819-02
NCGC00014819-03
NCGC00097920-01
AS-45535
NCI60_003280
ST078406
SY023155
2-(pyridin-4-yl)quinoline-4-carboxylicacid
DB-042620
CS-0116568
4-Quinolinecarboxylic acid, 2-(4-pyridinyl)
EN300-00687
AB00088210-01
AB00088210-04
SR-01000908315
SR-01000908315-1
Z56792374
F1142-0435