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Bupivacaine

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Identification
Molecular formula
C18H28N2O
CAS number
2180-92-9
IUPAC name
2-(4-tert-butylphenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanamide
State
State

At room temperature, Bupivacaine is in a solid state, typically formulated into aqueous solutions for medical use.

Melting point (Celsius)
108.00
Melting point (Kelvin)
381.15
Boiling point (Celsius)
463.45
Boiling point (Kelvin)
736.60
General information
Molecular weight
288.44g/mol
Molar mass
288.4390g/mol
Density
1.0180g/cm3
Appearence

Bupivacaine typically appears as a white crystalline powder. It is very slightly soluble in water, but soluble in alcohol and chloroform.

Comment on solubility

Solubility of 2-(4-tert-butylphenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanamide

The solubility of the compound 2-(4-tert-butylphenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanamide is influenced by various factors due to its complex structure. Understanding this solubility can provide insights into its potential applications. Here are several key points to consider:

  • Polarity: The overall polarity of the molecule is affected by the presence of both hydrophobic (tert-butyl and phenyl groups) and hydrophilic (dimethylamino group) elements. This biphasic nature often leads to moderate solubility in organic solvents while exhibiting lower solubility in water.
  • Solvent Interaction: This compound may show varied solubility in different solvents, displaying increased solubility in solvents like ethanol and acetone, while having reduced or negligible solubility in non-polar solvents.
  • Temperature Dependence: Like many organic compounds, its solubility can increase with temperature, enhancing the likelihood of dissolution in solution.
  • Potential for Formulation: Given its unique structure, this compound may have utility in pharmaceutical formulations where solubility is crucial for bioavailability.

In summary, the solubility characteristics of this compound are complex and depend heavily on the solvent choice and temperature conditions. Understanding these nuances is vital for effectively utilizing this compound in various applications.

Interesting facts

Interesting Facts about 2-(4-tert-butylphenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanamide

This compound, more commonly known in the field of chemistry for its unique structure and potential applications, belongs to a fascinating class of molecules. It features a complex arrangement of functional groups that confer specific properties and activities. Here are some intriguing aspects of this compound:

  • Pharmacological Potential: Compounds like this one often exhibit biological activity, making them candidates for drug development. Their unique structures can influence pharmacokinetics and efficacy.
  • Culture of Research: The process of synthesizing such structurally diverse compounds is a subject of great interest in organic chemistry research, often leading to novel discoveries in medicinal chemistry.
  • Dimethylamino Group: The presence of the dimethylamino group is critical, as it can enhance solubility and interaction with biological targets, allowing for better absorption in therapeutic contexts.
  • Synthetic Versatility: The synthetic pathways leading to this compound involve advanced organic transformations, showcasing the versatility and ingenuity of chemists in designing complex molecules.
  • Structural Diversity: The tert-butyl group adds bulk and steric hindrance, which may influence the compound's ability to interact with other molecules, thus affecting its intended application.

As we study such compounds, it is crucial to remember that their structure-activity relationship (SAR) often determines their effectiveness in real-world applications. Exploring the intricate connections between structure and function paves the way for innovative breakthroughs in various fields.

In the words of renowned chemist Linus Pauling, "The best way to have a good idea is to have lots of ideas." This axiom resonates with the ongoing exploration of chemical compounds like 2-(4-tert-butylphenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanamide.

Synonyms
BRN 2137835
2-(p-tert-Butylphenyl)-4-(dimethylamino)-2-isopropylbutyramide
14780-20-2
BUTYRAMIDE, 2-(p-tert-BUTYLPHENYL)-4-(DIMETHYLAMINO)-2-ISOPROPYL-
DTXSID40933222
2-(4-tert-Butylphenyl)-2-[2-(dimethylamino)ethyl]-3-methylbutanimidic acid