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Bupropion

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Identification
Molecular formula
C13H18ClNO
CAS number
31677-93-7
IUPAC name
2-(4-tert-butylphenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanenitrile
State
State

At room temperature, bupropion is in the form of a solid. The substance is typically supplied as a hydrochloride salt to enhance its stability and solubility.

Melting point (Celsius)
90.00
Melting point (Kelvin)
363.15
Boiling point (Celsius)
260.00
Boiling point (Kelvin)
533.15
General information
Molecular weight
239.33g/mol
Molar mass
239.3250g/mol
Density
0.2564g/cm3
Appearence

Bupropion appears as a white, crystalline powder. It is highly water-soluble and has a bitter taste. The substance is generally odorless.

Comment on solubility

Solubility of 2-(4-tert-butylphenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanenitrile

The solubility of 2-(4-tert-butylphenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanenitrile can be understood through several key aspects:

  • Polarity: The presence of the dimethylamino group introduces some polar character to the compound, which may enhance its solubility in polar solvents.
  • Hydrophobicity: The tert-butyl group contributes significant hydrophobic characteristics, which could reduce solubility in aqueous environments.
  • Solvent Dependence: Solubility is likely to vary significantly depending on the specific solvent used. For example, it may be more soluble in organic solvents such as ethanol or acetone rather than water.

In summary, the solubility of this compound can be described as being moderately soluble in organic solvents with limitations in aqueous solutions. Factors such as molecular structure and interactions with solvents play a crucial role in determining its solubility behavior.

Interesting facts

Interesting Facts about 2-(4-tert-butylphenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanenitrile

This compound, with a complex name that hints at its intricate structure, is notable for its fascinating applications and properties. Here are some interesting aspects that make it stand out in the world of chemistry:

  • Versatile Applications: This compound is often utilized in organic synthesis and can serve as a valuable intermediate in the manufacture of pharmaceuticals and agrochemicals. Its unique structure allows it to participate in various chemical reactions, making it a key player in research and industry.
  • Catalytic Role: It is recognized for its role in catalytic systems where it can enhance reaction rates, owing to the steric and electronic attributes of the tert-butyl and dimethylamino groups it possesses.
  • Electron Donor Characteristics: The presence of the dimethylamino group makes this compound an effective electron donor, which is crucial in many organic and medicinal chemistry applications. Such characteristics can enhance its reactivity in nucleophilic substitution reactions.
  • Structural Diversity: By varying the substituents, scientists can tailor the properties of this compound to optimize its performance in specific applications. This aspect of molecular design is fundamental in drug discovery and materials science.
  • Research Implications: The study of compounds like this one often leads to insights into reaction mechanisms and may pave the way for developing novel materials with advanced functionalities.

The synthesis and application of 2-(4-tert-butylphenyl)-2-[2-(dimethylamino)ethyl]-3-methyl-butanenitrile illustrate the exciting intersection of organic chemistry and material science. As researchers continue to explore its properties and potentials, this compound undoubtedly holds a wealth of knowledge and opportunities for innovation.

Synonyms
BRN 2135103
2-(p-tert-Butylphenyl)-4-(dimethylamino)-2-isopropylbutyronitrile
14795-40-5
BUTYRONITRILE, 2-(p-tert-BUTYLPHENYL)-4-(DIMETHYLAMINO)-2-ISOPROPYL-
DTXSID50933253
2-(4-tert-butylphenyl)-2-[2-(dimethylamino)ethyl]-3-methylbutanenitrile