Interesting facts
Interesting Facts about 2-[[4-(thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid
2-[[4-(thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid is a notable compound that has gained attention in the fields of medicinal chemistry and material science. Here are some compelling insights into this intriguing chemical:
- Structure and Functionality: This compound features an intricate structure that includes a benzoic acid backbone along with a carbamoyl group and a thiazole moiety. The presence of the sulfonamide functional group is particularly significant as it plays a crucial role in biological activity.
- Biological Relevance: Compounds containing sulfonamide groups, like this one, are often studied for their antibacterial properties. Their ability to inhibit bacterial growth makes them subjects of interest in pharmaceutical applications.
- Potential Applications: Beyond antibacterial potential, such compounds are being researched for their roles in targeting various diseases, including cancers. The thiazole ring may enhance the compound's ability to interact with biological targets.
- Research Significance: Studies have indicated that derivatives of benzoic acid can exhibit anti-inflammatory and analgesic properties, making them potentially useful in pain management therapies.
- Impact on Drug Development: The incorporation of heterocyclic moieties such as thiazole may significantly increase the efficacy of drugs, paving the way for novel therapeutic agents that could improve patient outcomes.
In summary, 2-[[4-(thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid is not just a chemical entity; it is a promising candidate for further research and development in drug discovery. As the field of medicinal chemistry evolves, compounds like this could play a vital role in addressing some of the most challenging health issues.
Synonyms
phthalylsulfathiazole
85-73-4
Sulfathalidine
Phthalylsulphathiazole
Phthalazol
Phthalylsulfonazole
Cremothalidine
Sulphaphthalyl
Phthalazole
Sulfaphthalazole
Phthalylnorsulfazole
Enteramida
Entexidina
Phtalazol
Intestiazol
Phthalidin
Sulfacetil
Thalistanin
Thalistatyl
Ultratiazol
Ftalazol
Ftalysept
Sulftalyl
Taleudron
Talidine
Taloudron
Thalazole
Thalinil
Entero-sulfina
N4-Phthalylsulfathiazole
Ftalil-Esteve
Ftalil-Septol
Phthaloylsulfathiazole
Phtalylsulfathiazol
AFI-Ftalyl
Entexidin
Ftalilsulfatiazol
4'-(2-Thiazolylsulfamyl)phthalanilic acid
Phthalylsulfathiazolum
4'-(2-Thiazolylsulfamoyl)phthalanilic acid
Ftalilsofatiazolo
Ftalylsulfathiazol
Ftalilsofatiazolo [DCIT]
2-(p-N-Phthalylsulfanilyl)aminothiazole
Phthalylsulfathiazole [INN]
2-(p-Phthalylaminobenzenesulfamido)thiazole
2-((4-(N-(Thiazol-2-yl)sulfamoyl)phenyl)carbamoyl)benzoic acid
2-(N4-Phthalylaminobenzenesulfonamide)thiazole
Ftalilsulfatiazol [INN-Spanish]
Phtalylsulfathiazol [INN-French]
(o-Carboxybenzoyl)-p-aminophenylsulfonamidothiazole
2-(N(sup4)-Phthalylsulfanilamido)thiazole
Phthalylsulfathiazolum [INN-Latin]
2-(N(sup 4)-Phthalylsulfanilamido)thiazole
Sulfaphtalylthiazol
EINECS 201-627-4
NSC 66454
NSC-66454
NSC 683525
NSC-683525
Phthalylsulfhathiazole
CHEBI:9336
DTXSID8023470
2-(N(sup 4)-Phthalyaminobenzenesulfonamide)thiazole
2-(N(sup 4)-Phthalyaminobenzenesulfonamido)thiazole
AI3-18632
UNII-6875L5852V
2-(N4-phthalylsulfanilamido)thiazole
Phthalanilic acid, 4'-(2-thiazolylsulfamoyl)-
Sulfanilamide, N(sup 4)-(o-carboxybenzoyl)-N'-2-thiazolyl-
Phthalylsulfathiazole [USP:INN:BAN]
2-[[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid
2-({4-[(1,3-thiazol-2-yl)sulfamoyl]phenyl}carbamoyl)benzoic acid
Phthalylsulfathiazole (INN)
Benzoic acid, 2-(((4-((2-thiazolylamino)sulfonyl)phenyl)amino)carbonyl)-
Benzoic acid, 2-[[[4-[(2-thiazolylamino)sulfonyl]phenyl]amino]carbonyl]-
MLS002693575
DTXCID203470
2-[[4-(thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid
85-73-4 (free)
Phthalazolum
6875L5852V
PHTHALYLSULFATHIAZOLE [MI]
EC 201-627-4
2-[[[4-[(2-Thiazolylamino)sulfonyl]phenyl]amino]carbonyl]benzoic acid
NSC66454
PHTHALYLSULFATHIAZOLE [MART.]
NSC683525
PHTHALYLSULFATHIAZOLE [WHO-DD]
CAS-85-73-4
NCGC00016337-02
PHTHALYLSULFATHIAZOLE [EP MONOGRAPH]
2-{[4-(1,3-thiazol-2-ylsulfamoyl)phenyl]carbamoyl}benzoic acid
2-(N4-phthalylaminobenzenesulfonamido)thiazole
Sulfanilamide, N4-(o-carboxybenzoyl)-N'-2-thiazolyl-
Ftalilsulfatiazol (INN-Spanish)
Phtalylsulfathiazol (INN-French)
Phthalylsulfathiazolum (INN-Latin)
PHTHALYLSULFATHIAZOLE (MART.)
Phthalylsulfathiazole (USP:INN:BAN)
2-[({4-[(1,3-thiazol-2-ylamino)sulfonyl]phenyl}amino)carbonyl]benzoic acid
Ftalylsulfathiazol [Czech]
SMR001233366
PHTHALYLSULFATHIAZOLE (EP MONOGRAPH)
SR-05000001793
2-((4-(thiazol-2-ylsulfamoyl)phenyl)carbamoyl)benzoic acid
2-((4-((1,3-thiazol-2-yl)sulfamoyl)phenyl)carbamoyl)benzoic acid
ftalilsulfatiazolo
2-(((4-((2-Thiazolylamino)sulfonyl)phenyl)amino)carbonyl)benzoic acid
phthalylsulfathiazol
phthalylsulphthiazole
Prestwick_980
MFCD00005318
Phthalylsulphathiozole
Spectrum_000047
Prestwick0_000869
Prestwick1_000869
Prestwick2_000869
Prestwick3_000869
Spectrum3_001486
Spectrum4_000154
Spectrum5_001147
component of Sulfathalidine
Oprea1_620492
BSPBio_000917
BSPBio_003071
KBioGR_000628
KBioSS_000427
MLS002154042
DivK1c_001029
SCHEMBL152662
SPECTRUM1502021
SPBio_002838
BPBio1_001009
Phthalylsulfathiazole (Standard)
CHEMBL1524273
HMS503M19
HY-B1407R
KBio1_001029
KBio2_000427
KBio2_002995
KBio2_005563
KBio3_002571
A07AB02
NINDS_001029
HMS1570N19
HMS1921D22
HMS2092N19
HMS2097N19
HMS2230G21
HMS3374A01
HMS3714N19
Pharmakon1600-01502021
HY-B1407
STR05252
Tox21_110380
NSC758159
s5700
STK730435
WLN: T5N CSJ BMSWR DMVR BVQ
AKOS000745948
Tox21_110380_1
CCG-212977
CS-4862
DB13248
FP40968
NSC-758159
IDI1_001029
NCGC00016337-01
NCGC00016337-03
NCGC00016337-05
NCGC00094943-01
NCGC00094943-02
AC-19044
SBI-0051702.P002
SBI-0051702.P003
DB-056881
AB00052257
NS00007465
T0703
C07659
D02440
D78257
AB00052257_08
EN300-18202568
N-(4-thiazol-2-ylsulfamoyl-phenyl)-phthalamic acid
Q4493189
SR-05000001793-1
SR-05000001793-3
BRD-K64659768-001-04-5
BRD-K64659768-001-12-8
BRD-K64659768-001-13-6
Z55165221
2-(4-(N-thiazol-2-ylsulfamoyl)phenylcarbamoyl)benzoic acid
N4-Phthalylsulfathiazole, VETRANAL(TM), analytical standard
2-((4-[(1,3-Thiazol-2-ylamino)sulfonyl]anilino)carbonyl)benzoic acid #
2-[[[4-[(2-Thiazolylamino)sulfonyl]phenyl]amino]carbonyl]-benzoic acid
Phthalylsulfathiazole, European Pharmacopoeia (EP) Reference Standard
201-627-4
Solubility of 2-[[4-(thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid (C16H14O3)
The solubility of 2-[[4-(thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid can be influenced by several factors due to its complex structure. Understanding its solubility is crucial for various applications in pharmaceuticals and materials science.
Key Points on Solubility:
In essence, while 2-[[4-(thiazol-2-ylsulfamoyl)phenyl]carbamoyl]benzoic acid may exhibit moderate solubility in polar solvents like water, its solubility can significantly increase in less polar organic solvents. The exact solubility values can only be determined through experimental studies, which would aid in understanding its behavior in biological and chemical systems.