Skip to main content

Flurbiprofen

ADVERTISEMENT
Identification
Molecular formula
C15H13O2S
CAS number
5104-49-4
IUPAC name
2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid
State
State

Flurbiprofen is a solid at room temperature, commonly found in the form of tablets or topical solutions for medical application.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.15
General information
Molecular weight
244.33g/mol
Molar mass
244.2690g/mol
Density
1.3200g/cm3
Appearence

Flurbiprofen typically appears as an off-white to white crystalline powder. It is odorless and somewhat soluble in water, more readily dissolving in alcohol and other organic solvents.

Comment on solubility

Solubility of 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid

The solubility of 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid (C15H13O2S), also known as a thiophene derivative, can be characterized based on its unique structural features and the presence of functional groups.

  • Polarity: The carboxylic acid group (-COOH) generally increases the polarity of the compound, leading to improved solubility in polar solvents such as water.
  • Aromatic nature: However, the presence of the aromatic thiophene ring and phenyl group tends to decrease overall solubility in water due to hydrophobic interactions. This implies that the compound is likely more soluble in organic solvents.
  • Solvent Compatibility: Typical solvents where this compound might be soluble could include ethanol, dimethyl sulfoxide (DMSO), and acetone.

In conclusion, while 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid is expected to exhibit some degree of solubility in polar solvents, its overall solubility profile will be primarily influenced by its hydrophobic aromatic components.

It is important to test solubility under various conditions to ascertain its application in different solvent systems.

Interesting facts

Interesting Facts About 2-[4-(thiophene-2-carbonyl)phenyl]propanoic Acid

This unique compound, 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid, merges the realms of organic chemistry and medicinal chemistry with its intriguing structure and potential applications. Here are some fascinating aspects of this compound:

  • Structural Diversity: The incorporation of a thiophene ring into the phenyl group provides this molecule with unique electronic and steric properties, which can influence its reactivity and interactions with other molecules.
  • Potential Biological Activity: Compounds containing thiophene moieties often exhibit significant biological activities, including anti-inflammatory and anti-tumor effects. This makes them intriguing candidates for drug development.
  • Application in Organic Synthesis: Its framework can serve as a valuable precursor or intermediate in the synthesis of more complex organic compounds, showcasing the utility of such derivatives in material science.
  • Research Interest: Scientists are continuously exploring the diverse roles of carboxylic acids in biological systems, leading researchers to study such compounds for their potential therapeutic benefits.

In the words of a chemist, “The unique features of compounds like 2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid are like keys waiting to unlock new pathways in the realm of drug discovery.” This highlights the importance of ongoing research in unveiling the full potential of such compounds.

At the intersection of chemistry and biology, this compound signifies the wonder of scientific exploration and the pursuit of innovation!

Synonyms
suprofen
40828-46-4
Profenal
Sutoprofen
p-2-Thenoylhydratropic acid
Masterfen
Maldocil
Suprol
Suprofene
Sulproltin
Suprofenum
Srendam
Topalgic
4-(2-Thenoyl)hydratropsaeure
Suprocil
Suprofene [INN-French]
Suprofenum [INN-Latin]
racemic suprofen
2-(4-(2-Thenoyl)phenyl)propionsaeure
p-(2-thenoyl)hydratropic acid
Suprofen (Profenal)
TN-762
2-[4-(thiophene-2-carbonyl)phenyl]propanoic acid
alpha-Methyl-4-(2-thienylcarbonyl)benzeneacetic acid
(+-)-2-(p-(2-Thenoyl)phenyl)propionic acid
TN 762
R-25061
2-(4-(thiophene-2-carbonyl)phenyl)propanoic acid
R-25,061
R 25061
(+/-)-Suprofen
CHEBI:9362
Suprofeno
NSC 303611
Hydratropic acid, p-(2-thenoyl)-
EINECS 255-096-9
UNII-988GU2F9PE
NSC-303611
988GU2F9PE
DTXSID5045469
Benzeneacetic acid, .alpha.-methyl-4-(2-thienylcarbonyl)-
CHEMBL956
Benzeneacetic acid, alpha-methyl-4-(2-thienylcarbonyl)-
DTXCID3025469
2-[4-(thiophen-2-ylcarbonyl)phenyl]propanoic acid
NSC303611
Suprofen [USAN:USP:INN:BAN:JAN]
Dolasteron
Suprofene (INN-French)
Suprofenum (INN-Latin)
SUPROFEN (MART.)
SUPROFEN [MART.]
SUPROFEN (USP-RS)
SUPROFEN [USP-RS]
2-[4-(Thiophene-2-carbonyl)-phenyl]-propionic acid
SUPROFEN (USP IMPURITY)
SUPROFEN [USP IMPURITY]
.alpha.-Methyl-4-(2-thienylcarbonyl)benzeneacetic acid
Profenol
Suprofen (USAN:USP:INN:BAN:JAN)
Profenal (TN)
SR-05000001776
2-(4-(thiophen-2-ylcarbonyl)phenyl)propanoic acid
2-(4-(Thiophene-2-carbonyl)-phenyl)-propionic acid
Suprofen (JAN/USP/INN)
TYN-762P
NCGC00016846-01
Prestwick_131
CAS-40828-46-4
MFCD00079572
Suprofen (Standard)
Spectrum_001157
SUPROFEN [USAN]
SUPROFEN [INN]
SUPROFEN [JAN]
SUPROFEN [MI]
SUPROFEN [VANDF]
(.+/-.)-Suprofen
Prestwick0_000816
Prestwick1_000816
Prestwick2_000816
Prestwick3_000816
Spectrum2_001430
Spectrum3_000928
Spectrum4_001027
Spectrum5_001103
Epitope ID:131797
SUPROFEN [WHO-DD]
2-(4-(2-Thienylcarbonyl)phenyl)propanoic acid
SCHEMBL23792
4-(2-Thenoyl)hydratropsaure
BSPBio_000711
KBioGR_001553
KBioSS_001637
MLS002154015
DivK1c_000476
SPECTRUM1501161
SPBio_001540
SPBio_002632
SUPROFEN [ORANGE BOOK]
4-(2-Thenoyl)hydratropic acid
BPBio1_000783
GTPL7298
Suprofen, >=98% (HPLC)
HMS501H18
HY-B0270R
KBio1_000476
KBio2_001637
KBio2_004205
KBio2_006773
KBio3_001936
M01AE07
NINDS_000476
GLXC-10240
HMS1570D13
HMS1921L19
HMS2092J07
HMS2097D13
HMS2232O08
HMS3372B18
HMS3651O17
HMS3714D13
HMS3754E05
HMS3884O08
Pharmakon1600-01501161
a-(p-thenoylphenyl) propionic acid
HY-B0270
(+)-p-(2-thenoyl)hydratropic acid
(-)-p-(2-thenoyl)hydratropic acid
Tox21_110643
BDBM50090676
CCG-38977
NSC757876
s1761
2-(4-(2-Thenoyl)phenyl)propionsaure
AKOS004909426
Tox21_110643_1
AC-4551
DB00870
NSC-757876
IDI1_000476
NCGC00094916-01
NCGC00094916-02
NCGC00094916-03
NCGC00094916-06
NCGC00094916-09
AS-15879
SMR001233343
DB-049665
AB00052231
NS00030853
SW196442-3
U0138
C07320
D00452
(+/-)-2-(p-(2-thenoyl)phenyl)propionic acid
AB00052231_08
EN300-7543068
(.+/-.)-2-(p-(2-Thenoyl)phenyl)propionic acid
2-[4-(2-Thienylcarbonyl)phenyl]propanoic acid #
Q3978097
SR-05000001776-1
SR-05000001776-3
2-{4-[(thiophen-2-yl)carbonyl]phenyl}propanoic acid
BRD-A34006693-001-04-8
BRD-A34006693-001-07-1
BRD-A34006693-001-14-7
BRD-A34006693-001-15-4
Z2587996507
Suprofen, United States Pharmacopeia (USP) Reference Standard
255-096-9