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Clonidine hydrochloride

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Identification
Molecular formula
C9H10ClFN3
CAS number
4205-91-8
IUPAC name
2-(4,5-dihydro-1H-imidazol-1-ium-2-ylmethyl)-4-fluoro-aniline;chloride
State
State

At room temperature, clonidine hydrochloride is typically found in a solid state.

Melting point (Celsius)
266.00
Melting point (Kelvin)
539.00
Boiling point (Celsius)
382.80
Boiling point (Kelvin)
656.00
General information
Molecular weight
266.13g/mol
Molar mass
266.1330g/mol
Density
1.3400g/cm3
Appearence

Clonidine hydrochloride typically appears as a white to off-white crystalline powder. The compound is hygroscopic in nature, meaning it tends to absorb moisture from the air.

Comment on solubility

Solubility of 2-(4,5-dihydro-1H-imidazol-1-ium-2-ylmethyl)-4-fluoro-aniline;chloride

The solubility of 2-(4,5-dihydro-1H-imidazol-1-ium-2-ylmethyl)-4-fluoro-aniline;chloride is an intriguing subject given its unique structural characteristics. As a chloride salt, this compound exhibits distinct solubility properties that can be understood through several factors:

  • Ionic Nature: Being a salt, its solubility in water is primarily influenced by its ionic components. Ionic compounds generally dissolve well in polar solvents, such as water, due to the interactions between the ions and the solvent.
  • Hydrophobic Interactions: The presence of the aromatic amine and the imidazolium structure may induce some hydrophobic characteristics. This could potentially affect its overall solubility as the non-polar portions of the molecule could hinder complete dissolution.
  • pH Dependence: The dissolution of this compound may also be sensitive to pH levels, as imidazolium compounds can participate in protonation or deprotonation reactions. This implies that solubility might increase under acidic conditions.
  • Temperature Effects: Like many salts, the solubility of this compound can vary with temperature, typically increasing as the temperature rises.

In summary, the solubility of 2-(4,5-dihydro-1H-imidazol-1-ium-2-ylmethyl)-4-fluoro-aniline;chloride can be anticipated to be influenced by its ionic nature, structural features, pH, and temperature. As explored in various studies, understanding these parameters is pivotal for applications in pharmaceutical and chemical industries.

Interesting facts

Interesting Facts about 2-(4,5-Dihydro-1H-Imidazol-1-ium-2-ylmethyl)-4-fluoro-aniline; Chloride

The compound 2-(4,5-dihydro-1H-imidazol-1-ium-2-ylmethyl)-4-fluoro-aniline; chloride is a fascinating example in the realm of organic chemistry, showcasing the intricate relationships between structure and function. Here are some engaging insights:

  • Structural Complexity: This compound features a unique combination of an imidazolium ring and a fluoroaniline structure, demonstrating how diverse functional groups can come together to form complex molecules.
  • Hydrogen Bonding: The presence of the imidazolium component significantly contributes to the potential for strong hydrogen bonding, which can influence the compound's reactivity and interaction with biological systems.
  • Biological Relevance: Compounds similar to this one have been studied for their potential biological activities, including antimicrobial properties and their roles as drug candidates. This highlights the potential of this compound in pharmaceuticals.
  • Environmental Applications: The ability of fluoroaniline derivatives to interact with various environmental factors opens up possibilities for applications in environmental monitoring, such as sensing agents for pollutants.

As noted by one chemist, "The beauty of organic compounds lies in their complexity and potential for real-world applications." This compound exemplifies such potential by bridging the gap between fundamental research and practical utility.

In summary, 2-(4,5-dihydro-1H-imidazol-1-ium-2-ylmethyl)-4-fluoro-aniline; chloride is not just a chemical entity but a platform for exploration, from drug discovery endeavors to environmental science innovations.

Synonyms
NS00122633