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Metronidazole hydrochloride

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Identification
Molecular formula
C6H10N4O3S
CAS number
443-48-1
IUPAC name
2-(4,5-dihydro-1H-imidazol-1-ium-2-ylsulfanyl)ethyl-dimethyl-ammonium;dichloride
State
State

At room temperature, metronidazole hydrochloride is in a solid state. It is commonly available as a powder or in crystalline form, and is used mainly in its solid form for pharmaceutical preparations.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.20
Boiling point (Celsius)
712.50
Boiling point (Kelvin)
985.60
General information
Molecular weight
219.17g/mol
Molar mass
219.1670g/mol
Density
1.6960g/cm3
Appearence

Metronidazole hydrochloride appears as a crystalline, white to pale yellow solid. It is often used in its hydrochloride salt form for medications, ensuring better solubility.

Comment on solubility

Solubility of 2-(4,5-dihydro-1H-imidazol-1-ium-2-ylsulfanyl)ethyl-dimethyl-ammonium;dichloride

The solubility of the compound 2-(4,5-dihydro-1H-imidazol-1-ium-2-ylsulfanyl)ethyl-dimethyl-ammonium;dichloride is influenced by its ionic nature and the presence of multiple functional groups. This compound exhibits the following solubility characteristics:

  • Solvent Dependence: It is typically soluble in polar solvents, particularly in water due to the presence of ammonium and sulfate groups.
  • Temperature Influence: Solubility may increase with temperature, a common characteristic for many ionic compounds.
  • pH Sensitivity: The solubility might vary with changes in pH, as the protonation states change in a basic or acidic environment.

As a quaternary ammonium salt, it is expected that this compound can dissolve well in aqueous solutions, which often promotes its potential applications in biological systems. Overall, its amphipathic nature allows it to interact favorably with both polar and non-polar environments.

In conclusion, the solubility of this compound in various media can be critical for its use in synthesis and biological applications, illustrating the importance of understanding solubility properties in chemical research.

Interesting facts

Exploring 2-(4,5-Dihydro-1H-Imidazol-1-Ium-2-Ylsulfanyl)ethyl-Dimethyl-Ammonium Dichloride

This intriguing compound plays a significant role in various scientific fields, particularly in medicinal chemistry and materials science. Here are some captivating facts about this compound:

  • Biological Importance: This compound's structure is reminiscent of natural biomolecules, which makes it a valuable subject of study in drug design and development. It may exhibit activities that could lead to potential pharmaceutical applications.
  • Role as Ion Pair: The presence of the dimethyl-ammonium and dichloride moieties suggests it can function as an ionic compound, which may impact its solubility and interaction with other molecules significantly.
  • Flexibility in Structure: The presence of both an imidazole ring and a sulfanyl group allows this compound to adopt various conformations, impacting its biological and chemical reactivity.
  • Potential Applications: Due to its quaternary ammonium nature, it may exhibit surfactant properties, making it useful in formulations for detergents, disinfectants, or even in modifying surfaces in biomedical applications.
  • Synthetic Pathways: The synthesis of this compound could involve several interesting chemical reactions, including nucleophilic substitutions and cyclization reactions, providing a rich area for students and researchers interested in synthetic organic chemistry.

In conclusion, 2-(4,5-dihydro-1H-imidazol-1-ium-2-ylsulfanyl)ethyl-dimethyl-ammonium dichloride stands out due to its multifaceted applications and biological significance, making it a noteworthy compound in the realm of chemical research.

Synonyms
Ethanamine, 2-((4,5-dihydro-1H-imidazol-2-yl)thio)-N,N-dimethyl-, dihydrochloride
2-((4,5-Dihydro-1H-imidazol-2-yl)thio)-N,N-dimethylethanamine dihydrochloride
16181-75-2