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Psilocin hydrochloride

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Identification
Molecular formula
C12H18ClN3O3
CAS number
28652-42-4
IUPAC name
2-(4,5,6-trimethoxy-1H-indol-3-yl)ethylammonium;chloride
State
State

At room temperature, psilocin hydrochloride is typically found in a solid state. It is quite sensitive to environmental conditions and must be stored properly to maintain its stability.

Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
246.71g/mol
Molar mass
246.7100g/mol
Density
1.3000g/cm3
Appearence

Psilocin hydrochloride is a crystalline solid that can appear as a powder. It is often colorless to slightly off-white. It is commonly used in research and may degrade to various shades if exposed to light or air due to its instability.

Comment on solubility

Solubility of 2-(4,5,6-trimethoxy-1H-indol-3-yl)ethylammonium chloride

The solubility of 2-(4,5,6-trimethoxy-1H-indol-3-yl)ethylammonium chloride can be quite intriguing due to its structure and the presence of both organic and ionic components. Below are some important aspects of its solubility:

  • Solvent Dependence: This compound is likely to show increased solubility in polar solvents such as water, primarily due to the ionic chloride portion, which facilitates hydration and solvation.
  • Temperature Influence: Solubility is generally temperature-dependent; it is expected that higher temperatures will enhance the solubility of this compound, making it more favorable for physiological or experimental conditions.
  • Functional Groups: The presence of the trimethoxy groups may create hydrophilic interactions, potentially increasing solubility in organic solvents as well, such as methanol or ethanol.

It's important to note that solubility can vary significantly with pH levels. As a quaternary ammonium compound, it may exhibit different solubility behaviors under various acidic or basic conditions. In summary, while this compound appears to have beneficial solubility properties in various solvents, the precise solubility characteristics can be influenced by multiple factors, including temperature and solution composition.

Interesting facts

Interesting Facts about 2-(4,5,6-trimethoxy-1H-indol-3-yl)ethylammonium;chloride

This compound, known for its intriguing structure and biological significance, is part of a broader family of indole derivatives, which are known for their role in both natural and synthetic chemistry. Here are some fascinating insights about this compound:

  • Biological Relevance: The indole structure is pivotal in many biochemical systems. Compounds that contain indole are often found in various alkaloids, which have significant pharmacological properties.
  • Applications: Researchers are exploring its potential use in medicinal chemistry, particularly in the development of new therapeutic agents. Indole derivatives often exhibit activities such as anti-inflammatory, anticancer, and antimicrobial properties.
  • Synthesizing Complexity: The synthesis of this compound involves sophisticated organic chemistry techniques, highlighting the versatility and challenge of working with such intricate molecules.

Additionally, the presence of multiple methoxy groups contributes to the compound's electron-donating properties, enhancing its reactivity. Scientists often use these types of compounds to study their interactions with biological systems and to develop novel applications. The ammonium salt form, highlighted by the chloride counterion, can influence its solubility and stability, making it an exciting subject of study in both theoretical and applied chemistry.

In the words of renowned chemist Linus Pauling, “The secret of the world is that it is made of molecules.” Exploring compounds like 2-(4,5,6-trimethoxy-1H-indol-3-yl)ethylammonium;chloride allows chemists to unlock the secrets of molecular interactions and their profound effects on life and technology.

Synonyms
4,5,6-Trimethoxytryptamine
5376-34-1
2-(4,5,6-trimethoxy-1H-indol-3-yl)ethylazanium;chloride
3-(2-Aminoethyl)-4,5,6-trimethoxyindole
INDOLE, 3-(2-AMINOETHYL)-4,5,6-TRIMETHOXY-, HYDROCHLORIDE