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Kanamycin A

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Identification
Molecular formula
C18H36N4O11
CAS number
59-01-8
IUPAC name
2-[4,6-diamino-3-[3-amino-5-hydroxy-6-(methylaminomethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-5-methyl-4-(methylamino)tetrahydropyran-3,5-diol
State
State

At room temperature, Kanamycin A is in a solid state, commonly found as a crystalline powder.

Melting point (Celsius)
256.00
Melting point (Kelvin)
529.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
484.48g/mol
Molar mass
484.4780g/mol
Density
1.6709g/cm3
Appearence

Kanamycin A appears as a white or almost white powder. It is typically sold in the form of its sulfate salt, which is also a white or nearly white water-soluble powder.

Comment on solubility

Solubility of 2-[4,6-diamino-3-[3-amino-5-hydroxy-6-(methylaminomethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-5-methyl-4-(methylamino)tetrahydropyran-3,5-diol

The solubility of the compound C18H36N4O11 is influenced by various factors, including its molecular structure, functional groups, and interactions with solvents. Here are some key points to consider:

  • Polar Functional Groups: The presence of multiple hydroxyl (-OH) groups, amino (-NH2), and ether functionalities suggests that the compound is likely to exhibit good solubility in polar solvents, particularly water.
  • Molecular Weight: With a relatively high molecular weight, the compound may exhibit limited solubility in non-polar solvents, which could otherwise hinder its dissolving ability.
  • Hydrogen Bonding: The ability of the compound to form hydrogen bonds can significantly enhance solubility in aqueous environments. This is particularly true for compounds containing amino and hydroxyl groups.
  • Temperature and pH Dependency: Solubility may also be affected by temperature and the pH of the solution, making it essential to consider these factors in practical applications.

In summary, it is reasonable to conclude that 2-[4,6-diamino-3-[3-amino-5-hydroxy-6-(methylaminomethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-5-methyl-4-(methylamino)tetrahydropyran-3,5-diol is likely to be soluble in water and other polar solvents due to its extensive functional groups that promote solvation through hydrogen bonding.

Interesting facts

Interesting Facts about 2-[4,6-diamino-3-[3-amino-5-hydroxy-6-(methylaminomethyl)tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-5-methyl-4-(methylamino)tetrahydropyran-3,5-diol

This complex chemical compound is a member of the tetrahydropyran family, which is well-regarded for its applications in medicinal chemistry and pharmaceuticals. Here are some fascinating insights into its properties and potential applications:

  • Structural Complexity: The compound showcases a unique structural architecture that includes multiple functional groups such as amines, hydroxyls, and ether linkages. This structural diversity can contribute to its biological activity.
  • Potential Therapeutic Uses: Compounds with similar frameworks are often investigated for their roles as potential drug candidates, particularly in the treatment of diseases like cancer and bacterial infections.
  • Biological Activity: The presence of amino groups suggests that this compound may interact with biological targets such as enzymes or receptors, making it a subject of interest for pharmacological research.
  • Modularity: The ability to modify the functional groups on the tetrahydropyran ring allows chemists to fine-tune the compound's properties for specific therapeutic purposes.
  • Research Potential: The intricate design of such compounds often leads to interesting studies in fields such as drug design, molecular biology, and organic synthesis.

As a chemist, it's crucial to explore the roles of compounds like this in advancing our understanding of molecular interactions and their implications in biological systems. Engaging with their synthetic routes and functionalization pathways adds to the richness of chemical research.

In summary, the compound's multifaceted structure and potential for biological interaction make it a noteworthy subject within the realms of organic chemistry and pharmacology. As we continue to uncover the mysteries of such compounds, we pave the way for innovative solutions in medicine and technology.