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Kanamycin A

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Identification
Molecular formula
C18H36N4O11
CAS number
59-01-8
IUPAC name
2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-5-methyl-4-(methylamino)tetrahydropyran-3,5-diol
State
State
Kanamycin A is solid at room temperature. It is commonly supplied in a crystalline powder form suitable for precise measurements and solubility in water-based solutions.
Melting point (Celsius)
259.00
Melting point (Kelvin)
532.00
Boiling point (Celsius)
239.00
Boiling point (Kelvin)
512.00
General information
Molecular weight
582.57g/mol
Molar mass
582.5740g/mol
Density
1.4000g/cm3
Appearence
Kanamycin A is typically encountered as a white to off-white powder. It is known for being hygroscopic, which means it can absorb moisture from the environment. This characteristic affects its storage conditions.
Comment on solubility

Solubility of 2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-5-methyl-4-(methylamino)tetrahydropyran-3,5-diol

The solubility of the compound with the chemical formula C18H36N4O11 can be discussed in terms of its unique structure and the interactions that arise from it. Here are some key points to consider:

  • Hydrophilicity vs. Hydrophobicity: The compound contains multiple hydroxyl (–OH) and amino (–NH2) groups, which tend to enhance its ability to interact with water. This suggests a potential for high solubility in aqueous solutions.
  • Polarity: Due to the presence of numerous polar functional groups, the overall polarity of the compound is expected to be significant, which can further facilitate solvation in polar solvents.
  • Temperature Dependency: As with many chemical compounds, solubility can be influenced by temperature. Generally, an increase in temperature may lead to an increase in solubility, especially for solid compounds.
  • pH Influence: The amino groups may become protonated or deprotonated depending on the pH of the solution, which could affect the compound's solubility, indicating that it may be soluble in a range of pH environments.
  • Solvent Compatibility: While the compound is likely to have favorable solubility in polar solvents like water, its solubility might significantly decrease in non-polar solvents owing to its hydrophilic character.

In summary, the intricate balance of polar and non-polar elements in the structure of this compound suggests that it has a good potential for solubility in polar solvents, while still being subject to varying conditions like temperature and pH that could enhance or limit that solubility. This complexity makes the study of its solubility an interesting topic for further exploration!

Interesting facts

Interesting Facts about 2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]-5-methyl-4-(methylamino)tetrahydropyran-3,5-diol

This fascinating compound is a complex organic molecule that plays a significant role within the field of medicinal chemistry and biochemistry. Due to its intricate structure, it poses unique properties and potential applications:

  • Chemical Diversity: The compound contains various functional groups, including amino, hydroxy, and ether groups. This diversity allows for a wide range of interactions with biological systems.
  • Bioactive Potential: Compounds similar to this one have been studied for their potential pharmacological effects, making them candidates for drug development. They could exhibit activity against diseases through various mechanisms of action.
  • Structure-Activity Relationship (SAR): Researchers can explore how modifications in the compound affect its biological activity. Studying SAR is crucial for optimizing drug efficacy.
  • Polyfunctional Nature: The presence of multiple amino groups could lead to interesting interactions with enzymes and receptors, providing opportunities for targeted therapies.

Overall, the study of such chemically intricate compounds is vital as they pave the way for advancements in therapeutic agents. As one scientist remarked, “The complexity often reflects the beauty of chemistry and its potential to unlock new dimensions in medicine.”

Synonyms
gentamicin
Cidomycin
Gentamicina
Gentamicinum
Gentamycinum
1403-66-3
Refobacin TM
Gentamicine
Gentamicins
Gentamycin-creme
Gentamycins
GENTAMYCIN
Oksitselanim
Centicin
Gentacycol
Lyramycin
Septigen
Gentamicine [INN-French]
Gentamicinum [INN-Latin]
Gentamicina [INN-Spanish]
HSDB 3087
UNII-T6Z9V48IKG
EINECS 215-765-8
2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
Gentamycin C1
T6Z9V48IKG
Gentamicin sulfate
Gentamicine (INN-French)
Gentamicinum (INN-Latin)
Gentamicina (INN-Spanish)
2-[4,6-diamino-3-[3-amino-6-(1-methylaminoethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-methylaminooxane-3,5-diol
Gentamycin-creme [German]
Genoptic S.O.P.
Gentamicin (TN)
Gentamicin (BAN)
Gentamicin [INN]
Gentamicin [INN:BAN]
Garamicin
Gentamycin Complex
Gentamicinum (Latin)
4,6-diamino-3-{[3-deoxy-4-c-methyl-3-(methylamino)pentopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside
SCHEMBL537630
CHEMBL329592
GTPL2427
DTXSID5034642
SCHEMBL19996168
CHEBI:17833
STL454325
AKOS015961211
DB00798
AC-13386
DA-63736
NS00002225
D08013
EN300-19875459
Q422482
1294497-75-8
2-{[4,6-diamino-3-({3-amino-6-[1-(methylamino)ethyl]oxan-2-yl}oxy)-2-hydroxycyclohexyl]oxy}-5-methyl-4-(methylamino)oxane-3,5-diol
215-765-8
4,6-diamino-3-(3-deoxy-4-C-methyl-3-(methylamino)pentopyranosyloxy)-2-hydroxycyclohexyl 2-amino-2,3,4,6,7-pentadeoxy-6-(methylamino)heptopyranoside