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Aclonifen

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Identification
Molecular formula
C12H10ClN3O2
CAS number
74070-46-5
IUPAC name
2-(4,6-dimethylpyrimidin-2-yl)-1-(4-nitrophenyl)guanidine
State
State

At room temperature, Aclonifen is a solid.

Melting point (Celsius)
77.50
Melting point (Kelvin)
350.50
Boiling point (Celsius)
576.00
Boiling point (Kelvin)
849.15
General information
Molecular weight
329.78g/mol
Molar mass
329.3190g/mol
Density
1.3800g/cm3
Appearence

Aclonifen is typically a yellowish solid. This compound has a crystalline structure and is usually found in powder form. The color can range from light yellow to pale yellow-brown depending on the concentration and form.

Comment on solubility

Solubility of 2-(4,6-dimethylpyrimidin-2-yl)-1-(4-nitrophenyl)guanidine

The solubility of 2-(4,6-dimethylpyrimidin-2-yl)-1-(4-nitrophenyl)guanidine is a crucial aspect to understand its potential applications in various fields. This compound is characterized by a complex molecular structure, influencing its behavior in solvents. Here are some key points regarding its solubility:

  • Solvent Polarity: The solubility of this compound tends to vary significantly based on the polarity of the solvent used. It is typically more soluble in polar solvents such as dimethyl sulfoxide (DMSO) or water.
  • pH Dependence: The solubility can also be affected by the pH of the solution, often increasing in acidic conditions due to protonation of the guanine moiety.
  • Temperature Effects: Like many organic compounds, solubility can enhance with an increase in temperature, allowing for greater molecular interactions with the solvent.
  • Crystal Structure: The solubility is influenced by the crystallinity of the compound. High crystal stability can lead to lower solubility unless disrupted by suitable solvents.

Understanding the solubility characteristics of 2-(4,6-dimethylpyrimidin-2-yl)-1-(4-nitrophenyl)guanidine is essential for optimizing its use in biochemical applications and drug formulation. As a general rule, like dissolves like, hence selecting the right solvent is critical for effective dissolution.

Interesting facts

Interesting Facts about 2-(4,6-Dimethylpyrimidin-2-yl)-1-(4-nitrophenyl)guanidine

2-(4,6-Dimethylpyrimidin-2-yl)-1-(4-nitrophenyl)guanidine is a fascinating compound that holds a significant place in the world of medicinal chemistry and organic synthesis. Here are some key points about this compound:

  • Pharmaceutical Applications: This compound has potential applications in pharmaceuticals, particularly as it may exhibit activity in treating various conditions due to the presence of the guanidine moiety, which is known for its bioactive properties.
  • Structural Diversity: The unique combination of the pyrimidine and nitrophenyl groups in its structure provides a diverse set of chemical functionalities. This versatility allows for various modifications, leading to a myriad of derivatives that can be synthesized.
  • Mechanism of Action: The guanidine functional group is known to interact with biological systems in distinct ways, such as acting as a base or forming hydrogen bonds, which can be crucial in developing new therapeutic agents.
  • Research Interest: Scientists are interested in compounds like this due to their potential role in drug design. Studies often focus on how slight modifications to the structure can impact biological efficacy and selectivity.
  • Synthetic Routes: The synthesis of this compound typically involves processes such as multi-step organic reactions, which can highlight the challenges and rewards of complex molecule design in chemistry.

As a chemistry student or researcher, exploring compounds like 2-(4,6-dimethylpyrimidin-2-yl)-1-(4-nitrophenyl)guanidine not only enhances your understanding of organic synthesis but also paves the way for discovering innovative solutions in drug development. Remember, as the famous chemist Linus Pauling said, "The best way to have a good idea is to have a lot of ideas." Embrace the multifaceted world of chemical compounds!

Synonyms
DTXSID10195799
4323-53-9
1-(4,6-Dimethyl-2-pyrimidinyl)-3-p-nitrophenylguanidine
DTXCID00118290
guanidine, 1-(4,6-dimethyl-2-pyrimidinyl)-3-(p-nitrophenyl)-
Cambridge id 5867262
CHEMBL1903718
1-(4,6-Dimethyl-2-pyrimidinyl)-3-(p-nitrophenyl)guanidine
HMS2521F13