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Fosfomycin

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Identification
Molecular formula
C3H7O4P
CAS number
23155-02-4
IUPAC name
[2-(4,8-dimethylnona-3,7-dienyl)-2-methyl-3-(2,6,10-trimethylundeca-1,5,9-trienyl)cyclopropyl]methyl phosphono hydrogen phosphate
State
State

At room temperature, Fosfomycin typically exists as a solid. It is a stable compound when kept in a controlled environment such as a well-sealed container to protect it from moisture.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
138.06g/mol
Molar mass
138.0590g/mol
Density
1.4000g/cm3
Appearence

Fosfomycin is a white or white crystalline powder. It is usually odorless and has a slightly sweet taste. When exposed to moisture, it is prone to hydrolyze and therefore must be stored in a dry environment.

Comment on solubility

Solubility of [2-(4,8-dimethylnona-3,7-dienyl)-2-methyl-3-(2,6,10-trimethylundeca-1,5,9-trienyl)cyclopropyl]methyl phosphono hydrogen phosphate

The solubility of the compound [2-(4,8-dimethylnona-3,7-dienyl)-2-methyl-3-(2,6,10-trimethylundeca-1,5,9-trienyl)cyclopropyl]methyl phosphono hydrogen phosphate (C3H7O4P) presents an intriguing profile due to its complex structure. Factors influencing its solubility include:

  • Polarity: The presence of the phosphono group increases the polarity of the compound, potentially enhancing its solubility in polar solvents such as water.
  • Hydrophobic Components: The long hydrocarbon chains attached to the cyclopropyl groups contribute to hydrophobicity, which may limit solubility in aqueous environments.
  • Temperature: Like most compounds, solubility can also be affected by temperature, with increased temperatures generally leading to greater solubility, especially in organic solvents.

However, the intricate structure and the presence of multiple substituents might result in variable solubility characteristics. Hence, it is essential to conduct empirical solubility tests under specific conditions to gain a clearer understanding of its behavior in different solvents.

In conclusion, while the compound exhibits properties conducive to solubility in polar solvents, its overall solubility will depend on a delicate balance between its polar and non-polar characteristics.

Interesting facts

Interesting Facts about [2-(4,8-dimethylnona-3,7-dienyl)-2-methyl-3-(2,6,10-trimethylundeca-1,5,9-trienyl)cyclopropyl]methyl phosphono hydrogen phosphate

This intriguing compound belongs to the class of phosphonates, which are notable for their applications in various fields, including agriculture and biochemistry. Here are some interesting points about this unique compound:

  • Structure and Complexity: The compound features a cyclopropyl group, which is a three-membered carbon ring. This structural component can introduce unique steric and electronic properties, influencing the reactivity and interactions of the molecule.
  • Biological Activity: Compounds like this one, with phosphono groups, are often investigated for their potential in the development of pharmaceuticals and agrochemicals. Their structural resemblance to naturally occurring substances may confer interesting biological properties.
  • Research Applications: The distinct features of phosphonates allow them to be used as inhibitors for enzymes and as research tools in metabolic pathways, particularly those involving nucleic acids.
  • Organic Synthesis: The synthesis of such complex phosphonate structures can serve as a testament to the advancements in organic chemistry techniques, showcasing various synthetic strategies including multi-step synthesis and protecting group chemistry.

As you delve into the study of this compound, consider the versatility of phosphonates and their significance in the larger context of chemical research. A well-known chemist once said, “Chemistry is the art of understanding the complex and simplifying the intricate,” which perfectly captures the essence behind studying such complex compounds.

In conclusion, the exploration of [2-(4,8-dimethylnona-3,7-dienyl)-2-methyl-3-(2,6,10-trimethylundeca-1,5,9-trienyl)cyclopropyl]methyl phosphono hydrogen phosphate not only enhances our understanding of phosphorus chemistry but also underscores its potential utility in various scientific domains.

Synonyms
DTXSID00865515
[2-(4,8-dimethylnona-3,7-dien-1-yl)-2-methyl-3-(2,6,10-trimethylundeca-1,5,9-trien-1-yl)cyclopropyl]methyl trihydrogen diphosphate