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Manzamine A

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Identification
Molecular formula
C37H44ClNO7
CAS number
104195-67-1
IUPAC name
[2-[(4R,8S,12R)-16-(2-chloroethoxy)-12-fluoro-19-formyl-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-16,18-dien-8-yl]-2-oxo-ethyl] acetate
State
State

Manzamine A is typically a solid at room temperature, manifesting in a highly crystalline form.

Melting point (Celsius)
268.00
Melting point (Kelvin)
541.15
Boiling point (Celsius)
593.00
Boiling point (Kelvin)
866.15
General information
Molecular weight
694.89g/mol
Molar mass
694.8880g/mol
Density
1.4700g/cm3
Appearence

Manzamine A typically appears as a crystalline solid. Its color may vary from a pale yellow to an off-white appearance, depending on the level of purity and specific synthesis process used.

Comment on solubility

Solubility of [2-[(4R,8S,12R)-16-(2-chloroethoxy)-12-fluoro-19-formyl-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-16,18-dien-8-yl]-2-oxo-ethyl] acetate

The solubility of a compound can play a critical role in its applications and behavior in various environments. When considering the solubility of [2-[(4R,8S,12R)-16-(2-chloroethoxy)-12-fluoro-19-formyl-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-16,18-dien-8-yl]-2-oxo-ethyl] acetate, several factors must be taken into account:

  • Molecular Structure: The complexity of its structure, with multiple functional groups and a large carbon framework, can influence how well this compound dissolves in various solvents.
  • Polarity: The presence of polar functional groups, such as the chloroethoxy and acetate groups, tends to enhance solubility in polar solvents like water and alcohols, whereas the hydrocarbon sharing in its structure may yield lower solubility in non-polar solvents.
  • Temperature Effects: Generally, solubility tends to increase with temperature, and it can be affected by altering the environmental conditions, such as pH and ionic strength.

To summarize:

  • Solubility highly depends on intermolecular interactions.
  • This compound is likely to be more soluble in polar solvents than in non-polar ones.
  • Experimental data would be necessary to determine its exact solubility characteristics.

In conclusion, understanding the solubility of this compound is essential for its effective utilization in chemical formulations and biological applications.

Interesting facts

Interesting Facts about 2-[(4R,8S,12R)-16-(2-chloroethoxy)-12-fluoro-19-formyl-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-16,18-dien-8-yl]-2-oxo-ethyl Acetate

This complex organic compound stands out due to its intricate structure and noteworthy applications. Here are some fascinating aspects of this compound:

  • Structural Complexity: The compound features a unique pentacyclic skeleton, characterized by five interconnected cyclic components. Such structures are often found in natural products and can exhibit diverse biological activities.
  • Fluorination: The incorporation of a fluorine atom enhances the lipophilicity of the molecule, which can improve its ability to penetrate biological membranes, making it an interesting candidate for drug development.
  • Chloroethoxy Group: The presence of a chloroethoxy substituent augments the compound's reactivity, allowing for potential chemical modifications that may lead to new derivatives with altered properties.
  • Biological Implications: Compounds with similar structural motifs have been studied for their anticancer, antiviral, and antifungal properties, highlighting the potential pharmaceutical relevance of this molecule.
  • Synthesis Challenges: The synthesis of such a complex compound typically involves multiple steps, each with specific conditions and reagents. Mastering synthetic strategies is crucial for chemists exploring similar compounds.

As one researcher aptly put it, *“The beauty of chemistry lies in the complexity of its compounds and the myriad ways we can manipulate them for beneficial purposes.”* This compound embodies that philosophy, encouraging further exploration into its properties and applications.


Through studying and understanding compounds like this, chemists gain insights into not only the molecular world but also the endless possibilities for innovation in fields such as medicinal chemistry and materials science.

Synonyms
SCHEMBL4354