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2,2'-Bi-1,3-benzoxazole

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Identification
Molecular formula
C16H10N2O2
CAS number
21235-52-3
IUPAC name
2-[5-(1,3-benzoxazol-2-yl)-2-thienyl]-1,3-benzoxazole
State
State

At room temperature, 2,2'-Bi-1,3-benzoxazole is in a solid state, typically found as a crystalline powder.

Melting point (Celsius)
217.00
Melting point (Kelvin)
490.15
Boiling point (Celsius)
460.00
Boiling point (Kelvin)
733.15
General information
Molecular weight
264.26g/mol
Molar mass
264.2900g/mol
Density
1.5000g/cm3
Appearence

The compound, 2,2'-Bi-1,3-benzoxazole, typically appears as a fine, off-white to light yellow powder.

Comment on solubility

Solubility of 2-[5-(1,3-benzoxazol-2-yl)-2-thienyl]-1,3-benzoxazole

The solubility of 2-[5-(1,3-benzoxazol-2-yl)-2-thienyl]-1,3-benzoxazole can be somewhat complex to evaluate due to its structural characteristics. This compound, often classified as an organic molecule, exhibits particular properties related to solubility in different solvents.

Factors Influencing Solubility:

  • Polarity: The presence of heteroatoms such as nitrogen and sulfur within the benzoxazole and thienyl rings can influence the polarity of the compound, impacting its solubility in polar vs. non-polar solvents.
  • Hydrophobic Interactions: The aromatic nature of the benzoxazole moieties suggests that the compound may have significant hydrophobic interactions, particularly when dissolved in non-polar organic solvents.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the nitrogen atoms may enhance solubility in polar solvents such as alcohols and water under certain conditions.

As a result, this compound may be sparingly soluble in water but could exhibit better solubility in organic solvents such as dimethyl sulfoxide (DMSO) or acetonitrile. Understanding the solubility characteristics can be crucial for applications in fields like drug formulation or materials science.

In summary, the solubility of 2-[5-(1,3-benzoxazol-2-yl)-2-thienyl]-1,3-benzoxazole is influenced by a variety of factors including polarity, hydrophobic interactions, and hydrogen bonding potential. Further experimental studies are warranted to fully characterize its solubility profile.

Interesting facts

Interesting Facts about 2-[5-(1,3-benzoxazol-2-yl)-2-thienyl]-1,3-benzoxazole

This fascinating compound, 2-[5-(1,3-benzoxazol-2-yl)-2-thienyl]-1,3-benzoxazole, belongs to the family of benzoxazoles, which are known for their diverse applications in medicinal chemistry and material science. Here are some intriguing insights:

  • Bioactivity: Compounds containing benzoxazole moieties often exhibit a range of biological activities, including anti-cancer, anti-inflammatory, and anti-microbial properties. This makes them a significant focus within pharmaceutical research.
  • Fluorescent Properties: Many benzoxazole derivatives are luminescent, which can be harnessed in applications such as fluorescence microscopy, making this compound potentially useful in biological imaging.
  • Electronic Applications: The incorporation of thiophene rings, as seen in this compound, often enhances the electronic properties, lending it utility in organic electronics, OLEDs, and photovoltaic devices.
  • Synthetic Versatility: Its structure allows for various chemical modifications. Scientists can modify the compound for specific functions or to enhance its properties, leading to customized applications.
  • Research Interest: According to recent studies, compounds similar to this one have shown promise in developing new therapeutic agents, driving ongoing research in chemical synthesis and drug design.

As a chemistry student, exploring compounds like 2-[5-(1,3-benzoxazol-2-yl)-2-thienyl]-1,3-benzoxazole can greatly enhance understanding of structure-activity relationships and inspire innovative solutions across multiple fields.

In the words of a notable chemist, "The beauty of chemistry lies not just in the compounds themselves, but in the endless possibilities they unlock for innovation."

Synonyms
2866-43-5
2,2'-Thiophene-2,5-diylbis(benzoxazole)
Benzoxazole, 2,2'-(2,5-thiophenediyl)bis-
2,5-BIS(2-BENZOXAZOLYL)THIOPHENE
12224-41-8
2,5-DI(Benzoxazol-2-YL)thiophene
TINOPAL SOP
P104CN84X2
C.I. Fluorescent Brightening Agent 185
DTXSID8051966
C.I. FLUORESCENT BRIGHTENER 172
C.I. 515240
2,2'-(2,5-THIOPHENEDIYL)BIS(BENZOXAZOLE)
DTXCID1030529
220-685-1
602-368-3
602-369-9
Fluorescent Brightener 185
Uvitex EBF
2,2'-(2,5-Thiophenediyl)bis-benzoxazole
Thiophenebis(benzoxazolyl)
SOF (fluorescent brightener)
2-[5-(1,3-benzoxazol-2-yl)thiophen-2-yl]-1,3-benzoxazole
2,5-Bis(2-benzoxazoyl)thiophene
Fluorescent brightener 185
Uvitex sof
Fba 185
C18H10N2O2S
2,5-Bis(benzoxazol-2-yl)thiophene
EINECS 220-685-1
Thiophene, 2,5-di(benzoxazol-2-yl)-
2,2'-(2,5-Thiophenediyl)bisbenzoxazole
C.I. Fluorescent brightening agent 190
SCHEMBL39752
CBDivE_007759
UNII-P104CN84X2
CHEMBL3694233
FBA-185
UGFSLKRMHPGLFU-UHFFFAOYSA-N
BDBM120341
HY-D0340
STK367333
AKOS005444378
2,5-di(benzo[d]oxazol-2-yl)thiophene
AS-75907
CS-0010345
NS00049345
2,2'-thiene-2,5-diylbis(1,3-benzoxazole)
US8703811, 83
A905135
BENZOXAZOLE,2,2'-(2,5-THIOPHENEDIYL)BIS-
Q27285976
Fluorescent Brightener 185(2866-43-5/12224-41-8 pound(c)