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Amiodarone

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Identification
Molecular formula
C25H29NO2
CAS number
19774-82-4
IUPAC name
2-[5-[3-(4-fluorophenyl)prop-2-enoyl]-4,7-dimethoxy-benzofuran-6-yl]oxyethyl-dimethyl-ammonium;4-hydroxy-4-oxo-but-2-enoate
State
State

Amiodarone is in a solid state at room temperature.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
335.90
Boiling point (Kelvin)
609.05
General information
Molecular weight
645.65g/mol
Molar mass
645.6480g/mol
Density
1.3495g/cm3
Appearence

Amiodarone is a white to slightly yellow crystalline powder.

Comment on solubility

Solubility of 2-[5-[3-(4-fluorophenyl)prop-2-enoyl]-4,7-dimethoxy-benzofuran-6-yl]oxyethyl-dimethyl-ammonium;4-hydroxy-4-oxo-but-2-enoate

The solubility of the compound 2-[5-[3-(4-fluorophenyl)prop-2-enoyl]-4,7-dimethoxy-benzofuran-6-yl]oxyethyl-dimethyl-ammonium;4-hydroxy-4-oxo-but-2-enoate can be influenced by various factors:

  • Polarity: This compound contains both polar and nonpolar groups, which can complicate its interaction with solvents. The presence of the ammonium group suggests potential solubility in polar solvents such as water.
  • Hydrogen bonding: The hydroxyl group (–OH) can participate in hydrogen bonding, enhancing its solubility in hydrogen bond donors like water.
  • Stocks and Conditions: The solubility is also dependent on the pH of the solution. In an acidic medium, the ammonium group could be protonated, potentially affecting the overall solubility.

As a result, while this compound may exhibit some degree of solubility in polar solvents, it is likely to have limited solubility in nonpolar solvents. Understanding its solubility behavior is essential for applications involving this compound, especially in biological systems where the solubility in aqueous environments is critical.

In conclusion, the solubility characteristics of this compound are best explored through empirical testing, considering the intricate balance of steric, electronic, and environmental factors that dictate solubility. Always remember, “Solubility is the key to unlocking the potential of a compound in solution.”

Interesting facts

Interesting Facts about 2-[5-[3-(4-fluorophenyl)prop-2-enoyl]-4,7-dimethoxy-benzofuran-6-yl]oxyethyl-dimethyl-ammonium;4-hydroxy-4-oxo-but-2-enoate

This compound is a fascinating example of synthetic organic chemistry that showcases the intricate connections between structural complexity and biological activity. Here are some interesting aspects:

  • Multifunctional Architecture: The structure of this compound includes a benzofuran moiety, which is known for its presence in various therapeutic agents. Its presence contributes to the compound's potential activity in medicinal chemistry.
  • Fluoro-substitution: The incorporation of a fluorophenyl group introduces unique electronic properties. Fluorine atoms can enhance the lipophilicity of the molecule, potentially affecting how the compound interacts with biological systems.
  • Dimethoxy Groups: The dimethoxy functional groups serve critical roles in influencing the compound's reactivity and solubility. Additionally, these groups may increase the overall stability of the compound.
  • Biodiversity in Activity: Compounds of this nature have been studied for their potential in anti-cancer therapies and other pharmacological applications, revealing their significance in drug discovery.
  • Synthetic Complexity: The synthesis of this compound illustrates the challenges chemists face. Creating compounds with precise functionalization requires advanced techniques and methodologies, such as cross-coupling reactions and selective protection/deprotection strategies.
  • Potential Applications: Given its structural characteristics, this compound might be explored for its role in various therapeutic areas, including anti-inflammatory and anti-viral effects.

In summary, the exploration and study of this compound not only expand our understanding of its potential biological implications but also highlight the artistry involved in modern synthetic organic chemistry. As researchers continue to investigate its characteristics, they may unlock new pathways for targeted therapies and enhancements in drug design.