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5-Hydroxytryptamine (serotonin) hydrochloride

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Identification
Molecular formula
C16H21Cl2N3O2
CAS number
153-98-0
IUPAC name
2-[5-(4-azaniumylbenzoyl)oxy-1H-indol-3-yl]ethylammonium;dichloride
State
State

The compound is typically in a solid state at room temperature. It is usually provided in either crystalline or powder form. Its physical state is stable under normal conditions of use and storage.

Melting point (Celsius)
210.00
Melting point (Kelvin)
483.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
327.17g/mol
Molar mass
327.1700g/mol
Density
1.2300g/cm3
Appearence

The compound typically appears as a white to off-white crystalline powder. Due to its hygroscopic nature, it can absorb moisture from the environment, potentially altering its appearance. It may also appear as fine crystals or crystalline powder that can clump together if exposed to moisture.

Comment on solubility

Solubility Characteristics of 2-[5-(4-azaniumylbenzoyl)oxy-1H-indol-3-yl]ethylammonium;dichloride

The solubility of 2-[5-(4-azaniumylbenzoyl)oxy-1H-indol-3-yl]ethylammonium;dichloride in various solvents is an important aspect to consider for its applications. This compound has both polar and nonpolar characteristics due to its complex structure, which influences its interactions with solvents.

Factors Affecting Solubility

Several factors contribute to the solubility of this compound:

  • Polarity: The presence of the ammonium group enhances polarity, which may increase solubility in polar solvents such as water and alcohols.
  • Hydrogen bonding: The ability to form hydrogen bonds due to functional groups enhances solubility in aqueous solutions.
  • Ion-dipole interactions: The dichloride salt form can facilitate solubility in polar aprotic solvents due to ion-dipole attractions.

Solubility Behavior

In practical terms, the solubility of 2-[5-(4-azaniumylbenzoyl)oxy-1H-indol-3-yl]ethylammonium;dichloride can be summarized as follows:

  • **Good solubility** in water due to its ionic nature.
  • **Moderate solubility** in alcohols and other polar solvents.
  • **Limited solubility** in nonpolar solvents, which is typical for compounds with significant polar characteristics.

In conclusion, the solubility profile of this compound is a reflection of its intricate structure and functional groups. Understanding these solubility characteristics can enhance its utility in various applications, particularly in biological and pharmaceutical contexts.

Interesting facts

Interesting Facts about 2-[5-(4-azaniumylbenzoyl)oxy-1H-indol-3-yl]ethylammonium;dichloride

This fascinating compound belongs to a class of molecules that often exhibit significant biological activities. Researchers are particularly interested in its potential applications in pharmaceuticals and materials science. Here are some compelling aspects of this compound:

  • Biological Significance: This compound features an indole moiety, which is well-known for its presence in many natural products and its role in medicinal chemistry. Indoles can exhibit a variety of biological activities, including anti-inflammatory and anti-cancer properties.
  • Potential for Drug Design: The azaniumylbenzoyl fragment suggests that this compound may interact with biological targets, making it a subject of interest in drug development. Compounds with similar structures have been explored for their efficacy in treating various diseases, such as cancer and neurodegenerative disorders.
  • Ionic Nature: The dichloride part of the compound indicates that it forms ionic bonds, which may influence its solubility and interaction with biological systems. This ionic character can enhance the compound's bioavailability and stability.
  • Complex Interactions: The presence of both an ammonium group and an indole structure suggests potential for complex interactions within biological systems. This can lead to unique mechanisms of action, which are crucial for the development of targeted therapies.
  • Material Applications: Beyond its biological implications, researchers are investigating similar compounds for use in sensors, organic electronics, and other advanced materials. The structural complexity often leads to interesting electronic properties.

“Chemical compounds like this one represent the bridge between molecular structure and functional diversity, paving the way for innovations in both health and technology.”

Overall, the exploration of 2-[5-(4-azaniumylbenzoyl)oxy-1H-indol-3-yl]ethylammonium;dichloride offers a glimpse into the intricate world of chemical research, where every compound has the potential to make a significant impact on diverse fields such as healthcare and materials science.

Synonyms
3-(2-Aminoethyl)indol-5-ol p-aminobenzoate dihydrochloride
19616-00-3
INDOL-5-OL, 3-(2-AMINOETHYL)-, p-AMINOBENZOATE (ester), DIHYDROCHLORIDE