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Melatonin Acetate

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Identification
Molecular formula
C13H19N2O2
CAS number
3167-55-1
IUPAC name
2-(5-benzoyloxy-1H-indol-3-yl)ethylammonium;acetate
State
State

Melatonin acetate is a solid at room temperature. It is stable under normal conditions and is typically stored in tightly sealed containers to prevent moisture absorption.

Melting point (Celsius)
117.00
Melting point (Kelvin)
390.15
Boiling point (Celsius)
383.20
Boiling point (Kelvin)
656.30
General information
Molecular weight
248.31g/mol
Molar mass
248.3090g/mol
Density
1.1790g/cm3
Appearence

Melatonin acetate is typically a white to off-white crystalline powder. It is known for its purity and consistency, which makes it useful in various scientific and pharmaceutical applications.

Comment on solubility

Solubility of 2-(5-benzoyloxy-1H-indol-3-yl)ethylammonium acetate

The solubility of 2-(5-benzoyloxy-1H-indol-3-yl)ethylammonium acetate can be considered based on its structural characteristics and the presence of functional groups. Understanding solubility is vital for applications in pharmaceuticals and chemical processes. Here are some key points regarding the solubility of this compound:

  • Polarity: The presence of the ammonium group suggests a degree of polarity, which can enhance solubility in polar solvents such as water.
  • Functional Groups: The acetate moiety often increases solubility in aqueous media, making the compound more soluble overall.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the indole structure may improve solubilization in certain environments.
  • Organic Solvents: This compound may also demonstrate solubility in organic solvents, though the degree will vary based on the solvent's characteristics.

In summary, while the exact solubility in specific solvents will depend on the conditions and solute concentrations, one could typically expect this compound to exhibit considerable solubility in both polar solvents like water and some organic solvents due to its unique structural features. As a result, it's advisable to evaluate solubility experimentally for practical applications.

Interesting facts

Interesting Facts about 2-(5-benzoyloxy-1H-indol-3-yl)ethylammonium Acetate

2-(5-benzoyloxy-1H-indol-3-yl)ethylammonium acetate is a fascinating compound that bridges the realms of organic chemistry and medicinal applications. Here are some insightful details that showcase its significance:

  • Indole Core: The compound features an indole moiety that is well-known for its presence in many biological systems and natural products. Indoles are significant due to their diverse pharmacological properties, including anti-cancer and anti-inflammatory activities.
  • Benzoyloxy Group: The incorporation of a benzoyloxy group enhances the compound's stability and can affect its interactions with biological targets. This functional group is also known for its ability to participate in various chemical reactions.
  • Ammonium Ion: The presence of the ethylammonium moiety implies that the compound can interact with biological membranes, which might contribute to its bioactivity. Compounds with ammonium groups are often considered in drug design for their solubility and permeability characteristics.
  • Potential Therapeutic Applications: Given the structure's resemblance to known pharmaceuticals, there is great interest in exploring its potential use in therapeutic applications, particularly in the fields of neurology and oncology.
  • Research Opportunities: The unique combination of functional groups opens avenues for the synthesis of analogs that could lead to compounds with improved efficacy or reduced side effects, making it a target for further research.

As a compound rich in potential, 2-(5-benzoyloxy-1H-indol-3-yl)ethylammonium acetate stands as a testament to the intricate relationship between chemical structure and biological activity. Its unique characteristics make it an enticing subject for both chemists and researchers aiming to uncover new therapeutic pathways.

Synonyms
3-(2-Aminoethyl)indol-5-ol benzoate monoacetate
18518-64-4
INDOL-5-OL, 3-(2-AMINOETHYL)-, BENZOATE (ester), MONOACETATE
DTXSID20171726
DTXCID2094217