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5-Benzyloxygramine

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Identification
Molecular formula
C17H18N2S
CAS number
53939-48-1
IUPAC name
2-(5-benzylsulfanyl-1H-indol-3-yl)ethanamine
State
State

At room temperature, 5-Benzyloxygramine is in a solid state.

Melting point (Celsius)
94.00
Melting point (Kelvin)
367.15
Boiling point (Celsius)
331.50
Boiling point (Kelvin)
604.65
General information
Molecular weight
270.40g/mol
Molar mass
270.3790g/mol
Density
1.2110g/cm3
Appearence

5-Benzyloxygramine is typically a crystalline solid. It may appear as off-white to pale yellow crystals or powder, depending on the level of purity and the specific form it is synthesized or isolated in.

Comment on solubility

Solubility of 2-(5-benzylsulfanyl-1H-indol-3-yl)ethanamine

The solubility of 2-(5-benzylsulfanyl-1H-indol-3-yl)ethanamine can be influenced by several factors that are crucial to understanding its behavior in different solvents. Here are some key points regarding its solubility:

  • Polarity: This compound has a significant amount of non-polar aromatic moieties, which can affect its solubility in polar solvents.
  • Solvent Interaction: Typically, compounds with bulky aromatic structures may show good solubility in organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO), while exhibiting lower solubility in water.
  • Temperature Influence: Like many organic compounds, the solubility may increase with temperature, making it easier to dissolve at elevated temperatures.
  • Functional Groups: The presence of the sulfonyl group may enhance hydrogen bonding interactions with certain solvents, affecting overall solubility.

It is essential to conduct empirical tests in specific solvents to determine the exact solubility profile, as theoretical predictions can often only provide estimations.

As a note, solvents such as dimethylformamide (DMF) can sometimes aid in solubilizing compounds with complex structures, so evaluating a range of solvents is recommended. Always remember, what works for one compound may not work for another!

Interesting facts

Interesting Facts about 2-(5-benzylsulfanyl-1H-indol-3-yl)ethanamine

The compound 2-(5-benzylsulfanyl-1H-indol-3-yl)ethanamine is a fascinating member of the indole family, which is known for its complex structure and diverse biological activities. Here are some key points that highlight its significance:

  • Complex Structure: It features a benzylsulfanyl group bonded to an indole, which is a bicyclic structure that incorporates a six-membered benzene ring fused to a five-membered nitrogen-containing pyrrole. This unique combination contributes to its intriguing chemical properties.
  • Biological Interest: Compounds containing the indole structure are often explored for their pharmacological properties. They have been implicated in roles such as being potential anti-cancer agents and neuroprotective compounds.
  • Reactivity: The presence of the ethylamine moiety can enhance reactivity in various chemical transformations, making this compound a valuable starting material for synthetic organic chemistry.
  • Connection to Natural Products: Indoles are commonly found in nature, especially in many tryptophan derivatives — an essential amino acid. This compound's structure echoes the complexity and beauty of natural products.
  • Research Applications: The unique features of this compound make it a candidate in research aimed at understanding receptor interactions, signaling pathways, and the development of therapeutic agents.

In conclusion, 2-(5-benzylsulfanyl-1H-indol-3-yl)ethanamine is not just a chemical entity but a gateway into the fascinating world of organic chemistry and medicinal research, showcasing the intricate relationship between structure and function in the development of new drug candidates.