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2-(5-bromobenzothiophen-3-yl)-N,N-dimethylethanamine

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Identification
Molecular formula
C12H14BrNS
CAS number
123635-35-0
IUPAC name
2-(5-bromobenzothiophen-3-yl)-N,N-dimethyl-ethanamine
State
State

This compound is typically a solid at room temperature, indicating stable physical characteristics under normal environmental conditions.

Melting point (Celsius)
85.40
Melting point (Kelvin)
358.60
Boiling point (Celsius)
336.50
Boiling point (Kelvin)
609.70
General information
Molecular weight
270.19g/mol
Molar mass
270.1870g/mol
Density
1.3600g/cm3
Appearence

The compound 2-(5-bromobenzothiophen-3-yl)-N,N-dimethyl-ethanamine typically appears as a solid at room temperature. The detailed color and form might vary depending on the specific batch and purity, typically appearing as a crystalline solid.

Comment on solubility

Solubility of 2-(5-bromobenzothiophen-3-yl)-N,N-dimethyl-ethanamine

The solubility of 2-(5-bromobenzothiophen-3-yl)-N,N-dimethyl-ethanamine is influenced by several factors due to its complex organic structure. When evaluating its solubility, consider the following characteristics:

  • Polarity: The presence of the thiophene ring and the bromine substituent can affect the compound's overall polarity, generally making it less soluble in polar solvents.
  • Solvent Interaction: It is likely more soluble in non-polar or weakly polar organic solvents, such as ethyl acetate or chloroform, due to the aromatic and aliphatic character of the compound.
  • Hydrogen Bonding: The amine group could facilitate hydrogen bonding in suitable solvents; however, steric hindrance from the dimethyl groups may hinder interactions with water.
  • Temperature Effects: As with many organic compounds, increasing the temperature may enhance the solubility by overcoming intermolecular forces.

Overall, while there may be some potential for solubility in organic solvents, its solubility in water is expected to be quite low due to the lipophilic nature of the compound.

Therefore, it is essential to consider the context of use and the solvent system when working with 2-(5-bromobenzothiophen-3-yl)-N,N-dimethyl-ethanamine.

Interesting facts

Interesting Facts about 2-(5-Bromobenzothiophen-3-yl)-N,N-Dimethyl-Ethanamine

2-(5-Bromobenzothiophen-3-yl)-N,N-dimethyl-ethanamine is a fascinating compound that merges the characteristics of both organics and heterocyclic chemistry. Here are some intriguing insights about this compound:

  • Structural Complexity: The presence of a bromobenzothiophene moiety contributes to the compound's distinct structural and electronic properties, making it noteworthy in the field of medicinal chemistry.
  • Potential Applications: This compound’s unique structure suggests potential use in pharmaceuticals, particularly as a scaffold for drug design aimed at targeting various receptors in the brain.
  • Synthetic Value: Compounds like this one are often synthesized through advanced organic reactions. Researchers might employ cross-coupling reactions or nucleophilic substitutions to introduce functional groups effectively.
  • Biological Interest: The incorporation of a bromine atom can enhance biological activity, as halogenated compounds often show increased affinity for biological targets, a principle widely exploited in drug discovery.
  • Research Relevance: Recent studies have shown that heteroaromatic amines, like this compound, can exhibit varied biological activities, including neuroprotective effects and potential anti-inflammatory properties.

As scientists delve deeper into the properties and applications of compounds like 2-(5-bromobenzothiophen-3-yl)-N,N-dimethyl-ethanamine, they uncover new horizons in both synthetic chemistry and pharmacology. The future of this compound may very well hold the key to innovative therapies and breakthroughs in drug development.


Synonyms
SCHEMBL8551337
XEZUDHLQTMLRQR-UHFFFAOYSA-N
AN-278/13643010
5-bromo-3-(N',N'-dimethyl-2-aminoethyl)benzothiophene
N-[2-(5-bromo-1-benzothien-3-yl)ethyl]-N,N-dimethylamine