2-[(5-bromopyridin-1-ium-2-yl)amino]-1-phenyl-ethanol;chloride

Identification

Molecular formula

C₁₃H₁₄BrClNO

CAS number

106467-37-6

IUPAC name

2-[(5-bromopyridin-1-ium-2-yl)amino]-1-phenyl-ethanol;chloride

State

The compound is commonly found in solid state at room temperature.

Melting point (Celsius)

188.00

Melting point (Kelvin)

461.15

Boiling point (Celsius)

313.00

Boiling point (Kelvin)

586.15

General information

Molecular weight

314.60g/mol

Molar mass

314.6030g/mol

Density

1.5000g/cm³

Appearence

This compound typically appears as a crystalline solid and may exhibit various colors depending on the specific sample. Its crystalline structure can vary from powder to fine granules.

Comment on solubility

Solubility of 2-[(5-bromopyridin-1-ium-2-yl)amino]-1-phenyl-ethanol; chloride

The solubility of 2-[(5-bromopyridin-1-ium-2-yl)amino]-1-phenyl-ethanol; chloride can be influenced by several factors such as temperature, pH, and the presence of other ions in the solution. Generally, ionic compounds have varying degrees of solubility in water, and in the case of this compound, it is expected to exhibit the following characteristics:

Polarity: Due to the presence of both a quaternary ammonium group and a chloride ion, this compound is likely to be highly polar, which enhances its solubility in polar solvents like water.
Hydrophilicity: The amino and hydroxyl groups contribute to the compound's ability to form hydrogen bonds with water, promoting solubility.
Temperature Effect: As with many compounds, solubility may increase with temperature, making warmer solvents more effective for dissolving this compound.
pH Sensitivity: The solubility may also be affected by the pH of the solution; for instance, under acidic or basic conditions, the ionization state of the functional groups could alter solubility.

In summary, 2-[(5-bromopyridin-1-ium-2-yl)amino]-1-phenyl-ethanol; chloride is expected to be soluble in polar solvents, particularly water, but the degree of solubility can vary based on environmental conditions. As always, it’s important to conduct empirical tests to confirm solubility in specific solvent systems.

Interesting facts

Interesting Facts about 2-[(5-bromopyridin-1-ium-2-yl)amino]-1-phenyl-ethanol; chloride

This compound is a member of a fascinating class of chemicals known as quaternary ammonium compounds. Often utilized in various fields, it exhibits unique chemical and biological properties that make it an area of interest for researchers.

Chemical Structure and Properties

The presence of a 5-bromopyridin-1-ium unit in its structure is particularly noteworthy. Brominated pyridines are known for their:

Increased reactivity: The bromine atom can participate in substitution reactions, making this compound valuable in synthetic chemistry.
Biological activity: Compounds featuring pyridine rings can exhibit diverse biological effects, which is why this compound has potential applications in pharmaceuticals.

Applications in Pharmacy and Biology

This compound has implications in:

Medicinal chemistry: Compounds derived from similar structures are frequently tested for their efficacy as drugs.
Antimicrobial properties: Its quaternary ammonium structure contributes to potential antibacterial and antifungal properties.

Research and Development

Interestingly, ongoing research may focus on:

Structure-activity relationship (SAR): Understanding how structural changes impact biological activity.
New derivatives: Exploring modifications that could enhance efficacy or reduce side effects in medicinal applications.

As noted by many researchers in the field: “The role of nitrogen-containing heterocycles in drug discovery cannot be underestimated.” This compound serves as a prime example of how such structures pave the way for innovation in medicinal chemistry.

Synonyms

alpha-(((5-Bromo-2-pyridyl)amino)methyl)benzyl alcohol hydrochloride

BENZYL ALCOHOL, alpha-(((5-BROMO-2-PYRIDYL)AMINO)METHYL)-, HYDROCHLORIDE

1023-23-0