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Tryptamine Hydrochloride

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Identification
Molecular formula
C11H14Cl2N2
CAS number
521-31-3
IUPAC name
[2-(5-chloro-1H-indol-3-yl)-1-methyl-ethyl]ammonium;chloride
State
State
Solid at room temperature with a crystalline form.
Melting point (Celsius)
246.00
Melting point (Kelvin)
519.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
292.20g/mol
Molar mass
292.1990g/mol
Density
1.3190g/cm3
Appearence

The compound appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of [2-(5-chloro-1H-indol-3-yl)-1-methyl-ethyl]ammonium;chloride

The solubility of the compound [2-(5-chloro-1H-indol-3-yl)-1-methyl-ethyl]ammonium;chloride, which is a quaternary ammonium salt, can be characterized by the following key aspects:

  • Polarity: Quaternary ammonium compounds tend to be polar, which generally enhances their solubility in polar solvents.
  • Solvent Compatibility: This compound is expected to have good solubility in water due to its ionic nature, specifically because the chloride ion (Cl) facilitates solvation.
  • Temperature Influence: The solubility of such salts typically increases with temperature, which can be an important factor during the preparation and application in various solutions.
  • pH Dependence: The solubility might also be influenced by the pH of the solution, as the protonation state of the ammonium group can vary based on the surrounding conditions.

In general, the presence of a chlorinated aromatic group may introduce some degree of hydrophobicity, but the overall ionic character predominates, leading to significantly favorable solubility characteristics in polar solvents. Hence, it's reasonable to conclude that [2-(5-chloro-1H-indol-3-yl)-1-methyl-ethyl]ammonium;chloride is likely to be quite soluble in water, making it versatile for various applications in chemical research and formulations.

Interesting facts

Interesting Facts about [2-(5-chloro-1H-indol-3-yl)-1-methyl-ethyl]ammonium;chloride

This intriguing compound belongs to a class of substances known for their biological activity and potential therapeutic applications. Often utilized in the field of medicinal chemistry, compounds like this one can possess important properties that contribute to the development of new pharmaceuticals.

  • Biochemical Significance: The indole ring structure is a critical motif in many natural products and drugs, known for its role in neurotransmission and potential anti-cancer effects.
  • Medicinal Properties: Compounds similar to this one are often investigated for their capacity to interact with neurotransmitter systems, particularly serotonin receptors, which are pivotal in mental health treatments.
  • Chlorination Influence: The presence of the chlorine atom can enhance the lipophilicity of the compound, impacting its bioavailability and interaction with biological membranes.

In the realm of synthetic chemistry, producing compounds like [2-(5-chloro-1H-indol-3-yl)-1-methyl-ethyl]ammonium;chloride can be both a challenge and a triumph. The ability to manipulate different functional groups allows chemists to explore vast landscapes of chemical reactivity:

  • Structural Modifications: Minor changes in the substituents can lead to significantly different biological activities, demonstrating the delicate balance of structure-activity relationships.
  • Research and Development: Ongoing studies aim to fully understand the mechanisms of action of such compounds, pushing the boundaries of knowledge in therapeutic applications.

As a notable example in the field of organic chemistry, this compound illustrates the blend of synthetic ingenuity and biological exploration. It underscores the complex interactions that can arise from even seemingly simple chemical formulas. Researchers continue to unlock the potential of these compounds, paving the way for advancements in drug discovery and development.

Synonyms
INDOLE, 3-(2-AMINOPROPYL)-5-CHLORO-, HYDROCHLORIDE
3-(2-Aminopropyl)-5-chloroindole hydrochloride
NSC 50457