Skip to main content

5-Chloro-α-methyltryptamine

ADVERTISEMENT
Identification
Molecular formula
C12H15ClN2
CAS number
21499-66-1
IUPAC name
2-(5-chloro-1H-indol-3-yl)-2-methyl-propan-1-amine
State
State

At room temperature, the compound is generally found in a solid state.

Melting point (Celsius)
127.50
Melting point (Kelvin)
400.65
Boiling point (Celsius)
348.80
Boiling point (Kelvin)
621.95
General information
Molecular weight
220.72g/mol
Molar mass
220.7200g/mol
Density
1.2500g/cm3
Appearence

The compound is typically observed as a crystalline solid, often appearing as colorless or pale white to slightly yellow crystals.

Comment on solubility

Solubility of 2-(5-chloro-1H-indol-3-yl)-2-methyl-propan-1-amine

The solubility of 2-(5-chloro-1H-indol-3-yl)-2-methyl-propan-1-amine can vary significantly depending on the solvent and environmental conditions. This compound, also referred to as a substituted indole derivative, presents unique solubility characteristics:

  • Solvent Dependency: Generally, organic compounds like this one may show higher solubility in non-polar solvents (e.g., hexane, toluene) and somewhat less solubility in polar solvents (e.g., water, methanol).
  • Functional Groups: The presence of both alkyl amine and aromatic ring structures can influence solubility. The amine group may enhance the solubility in polar media due to possible hydrogen bonding with solvents like water.
  • Temperature Influence: Solubility is often affected by temperature; typically, increasing temperature enhances the solubility of most solid compounds.

It is crucial to note that the specific conditions (like pH and presence of other solutes) can greatly impact solubility. As stated, "The beauty of chemistry lies in its complexities"—every compound has a unique behavior in different environments.

In practice, conducting solubility tests in various solvents can give a clearer picture of how 2-(5-chloro-1H-indol-3-yl)-2-methyl-propan-1-amine behaves, thus informing its application in pharmaceuticals and research.

Interesting facts

Interesting Facts about 2-(5-chloro-1H-indol-3-yl)-2-methyl-propan-1-amine

2-(5-chloro-1H-indol-3-yl)-2-methyl-propan-1-amine, often referred to simply as a chloroindole derivative, belongs to a fascinating class of compounds characterized by their structural complexity and biological significance. Here are some intriguing aspects of this compound:

  • Structural Versatility: The presence of both an indole ring and an amine group in the structure makes this compound a key player in medicinal chemistry, potentially serving as a scaffold for drug development.
  • Biological Activity: Compounds with indole derivatives have been studied for various pharmacological properties, including their role in antidepressant, anti-inflammatory, and anticancer activities.
  • Synthetic Pathways: The synthesis of chloroindole derivatives like this one is a significant topic in organic chemistry. The synthesis often involves methods such as coupling reactions and functional group modifications, providing a rich area for research and experimentation.
  • Environmental Significance: Indole and its derivatives often show up in natural products and biological systems, serving as precursors to a range of essential biological compounds, including hormones and neurotransmitters.
  • Research Investigations: Scientists are continually exploring the potential applications of compounds like 2-(5-chloro-1H-indol-3-yl)-2-methyl-propan-1-amine in the treatment of various diseases, making it a hot topic in current scientific literature.

In summary, the exploration of 2-(5-chloro-1H-indol-3-yl)-2-methyl-propan-1-amine not only highlights the intricate connections between structure and function in chemistry but also emphasizes the ongoing quest for novel therapeutic agents. As a **scientist** or **chemistry student**, delving into the properties and applications of such compounds can lead to significant discoveries and innovations.

Synonyms
BRN 0397126
14487-95-7
5-Chloro-beta,beta-dimethyltryptamine
INDOLE, 5-CHLORO-3-(2-AMINO-1,1-DIMETHYLETHYL)-
DTXSID90162828
DTXCID6085319
5-22-10-00185 (Beilstein Handbook Reference)
SCHEMBL9268928
QDTMEDNJIZALMQ-UHFFFAOYSA-N
[1-(5-chloro-1H-indol-3-yl)-1,1-dimethylethyl]amine