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Cimetidine

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Identification
Molecular formula
C10H16ClN5S
CAS number
51481-61-9
IUPAC name
2-[5-cyano-2-[(4-ethoxyphenyl)methyl]benzimidazol-1-yl]ethyl-diethyl-ammonium;chloride
State
State

At room temperature, cimetidine hydrochloride is typically found in a solid state.

Melting point (Celsius)
139.00
Melting point (Kelvin)
412.20
Boiling point (Celsius)
435.10
Boiling point (Kelvin)
708.30
General information
Molecular weight
252.35g/mol
Molar mass
252.3480g/mol
Density
1.2300g/cm3
Appearence

The compound is typically a solid in its pure form. It often appears as a white crystalline powder that is odorless.

Comment on solubility

Solubility of 2-[5-cyano-2-[(4-ethoxyphenyl)methyl]benzimidazol-1-yl]ethyl-diethyl-ammonium;chloride

The solubility characteristics of 2-[5-cyano-2-[(4-ethoxyphenyl)methyl]benzimidazol-1-yl]ethyl-diethyl-ammonium chloride are quite fascinating and can be influenced by several factors:

  • Polarity: The presence of both cationic ammonium and anionic chloride groups typically enhances solubility in polar solvents, particularly water.
  • Hydrogen Bonding: The functional groups within the molecule may participate in hydrogen bonding, which can further promote solubility in polar environments.
  • Solvent Interaction: While it tends to dissolve well in aqueous solutions, the degree of solubility could decrease in less polar solvents, making solvent choice critical.
  • Temperature Effects: As with many chemical compounds, increasing the temperature can often lead to an increase in solubility; thus, this compound may have higher solubility at elevated temperatures.

In conclusion, solubility is not just a binary concept but rather a complex interplay of molecular structure, solvent characteristics, and environmental conditions. As a result, understanding the solubility of this compound is vital for its effective application in various chemical contexts.

Interesting facts

Interesting Facts about 2-[5-Cyano-2-[(4-Ethoxyphenyl)methyl]benzimidazol-1-yl]ethyl-diethyl-ammonium; Chloride

This compound is a fascinating example of a quaternary ammonium salt that demonstrates unique characteristics and applications in the field of chemistry. Here are some intriguing aspects of this compound:

  • Structural Significance: The presence of the benzimidazole core is noteworthy; this bicyclic structure is renowned for its biological properties and has been studied extensively for its applications in pharmaceuticals.
  • Cyanide Group: The inclusion of the cyano group introduces significant reactivity, which can be harnessed in various chemical reactions. These groups are often involved in nucleophilic attacks and can serve as precursors for many synthetic pathways.
  • Ammonium Salts: As a quaternary ammonium compound, it exhibits amphiphilic properties, making it useful in applications such as surfactants, antimicrobial agents, and stabilization of emulsions.
  • Biological Activity: Compounds like this one are often assessed for their pharmacological potential. Research suggests that benzimidazole derivatives may exhibit anti-fungal, anti-viral, and even anti-cancer properties.
  • Medicinal Chemistry: The synthesis of this compound could lead to novel therapeutic agents, thus contributing to the ongoing efforts in developing medication for various ailments.

The multi-functional nature of this compound makes it a subject of interest not just in organic synthesis but also in medicinal chemistry. As scientists continue to explore its properties, the potential applications in drug development and industrial processes are becoming increasingly evident. “Understanding compounds with such complex structures is pivotal for discovering innovative solutions to modern health challenges.”

Synonyms
15419-87-1
1-(2-(Diethylamino)ethyl)-2-(p-ethoxybenzyl)-5-benzimidazolecarbonitrile hydrochloride
5-Benzimidazolecarbonitrile, 1-(2-(diethylamino)ethyl)-2-(p-ethoxybenzyl)-, monohydrochloride
2-[5-cyano-2-(4-ethoxybenzyl)-1H-benzimidazol-1-yl]-N,N-diethylethanaminium chloride