Skip to main content

DMT (N,N-Dimethyltryptamine)

ADVERTISEMENT
Identification
Molecular formula
C12H16N2
CAS number
61-50-7
IUPAC name
2-[5-(dimethylamino)-1H-indol-3-yl]acetonitrile
State
State

At room temperature, DMT is typically a solid in its pure form.

Melting point (Celsius)
46.00
Melting point (Kelvin)
319.15
Boiling point (Celsius)
160.00
Boiling point (Kelvin)
433.15
General information
Molecular weight
204.27g/mol
Molar mass
204.2800g/mol
Density
1.1160g/cm3
Appearence

DMT is typically found as a crystalline solid, ranging from white to slightly yellow. It is known to come in various forms such as freebase (powder), which is usually smoked, and salt (crystals), which is more often used orally or intravenously.

Comment on solubility

Solubility of 2-[5-(dimethylamino)-1H-indol-3-yl]acetonitrile

The solubility of 2-[5-(dimethylamino)-1H-indol-3-yl]acetonitrile can be described through several key factors:

  • Polarity: The presence of polar functional groups, such as the nitrile group (-C≡N) and the dimethylamino group (-N(CH3)2), contributes to its solubility in polar solvents.
  • Solvent Compatibility: This compound is likely to dissolve well in polar protic solvents like water and alcohols, while showing lower solubility in nonpolar solvents.
  • Temperature Effects: Elevated temperatures may improve solubility, as increased kinetic energy can disrupt solute-solvent interactions, allowing for greater solubility.

According to *solubility principles*, “like dissolves like,” which suggests that the structural characteristics of 2-[5-(dimethylamino)-1H-indol-3-yl]acetonitrile may favor solubility in polar environments, but could limit solubility in hydrophobic solvents.

In laboratory contexts, when assessing solubility, it is important to consider:

  1. Concentration ranges for effective dissolution.
  2. Environmental factors such as pH and ionic strength that may influence solubility.
  3. Potential formation of complexes or interactions with other solutes.

Overall, understanding the solubility characteristics of this compound is crucial for its application in various chemical reactions and formulations.

Interesting facts

Interesting Facts about 2-[5-(dimethylamino)-1H-indol-3-yl]acetonitrile

2-[5-(dimethylamino)-1H-indol-3-yl]acetonitrile is a fascinating compound that belongs to a class of chemicals known as indoles. Indoles are organic compounds composed of a fused benzene and pyrrole ring, which endows them with unique properties and biological activities.

Key Highlights:

  • Biological Activity: This compound has garnered attention in medicinal chemistry due to its potential in drug discovery. Indole derivatives often exhibit various pharmacological effects, making them a point of interest for researchers.
  • Structural Features: The presence of a dimethylamino group significantly influences the compound's reactivity and solubility, enhancing its bioactivity.
  • Application in Research: 2-[5-(dimethylamino)-1H-indol-3-yl]acetonitrile is commonly explored for its role in synthesizing other biologically relevant compounds.
  • Insights from Nature: The indole structure is prevalent in many natural compounds, including the amino acid tryptophan, and it's a key intermediate in numerous metabolic pathways.

As famously noted by William A. Miller, “The language of chemistry is intricate and fascinating, filled with symphonies of structures and reactions.” The study of 2-[5-(dimethylamino)-1H-indol-3-yl]acetonitrile exemplifies this intricate language, showcasing the interplay between structure and function in the world of organic compounds.

Research surrounding compounds like this one not only broadens our understanding of chemical interactions but also underscores the importance of indoles in advancing therapeutic applications and innovative synthetic methodologies.

Synonyms
3-INDOLEACETONITRILE, 5-DIMETHYLAMINO-
BRN 0397369
5-Dimethylamino-3-indoleacetonitrile
6843-24-9
DTXSID20218549
5-22-14-00009 (Beilstein Handbook Reference)
DTXCID20141040