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5-Fluoro-DMT

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Identification
Molecular formula
C11H13FN2
CAS number
88838-71-1
IUPAC name
2-(5-fluoro-1H-indol-3-yl)propan-1-amine
State
State

State at Room Temperature: 5-Fluoro-DMT is typically found as a solid under standard conditions. It is stable and crystalline in nature, making it easy to handle at room temperature.

Melting point (Celsius)
98.00
Melting point (Kelvin)
371.15
Boiling point (Celsius)
306.10
Boiling point (Kelvin)
579.25
General information
Molecular weight
194.23g/mol
Molar mass
194.2340g/mol
Density
1.2820g/cm3
Appearence

5-Fluoro-DMT is generally observed as a white to off-white crystalline powder when purified. It might also appear as a solid mass with slight variation in color depending on impurities.

Comment on solubility

Solubility of 2-(5-fluoro-1H-indol-3-yl)propan-1-amine

The solubility of 2-(5-fluoro-1H-indol-3-yl)propan-1-amine is influenced by several factors, including its molecular structure and polarity. Here are some key considerations regarding its solubility:

  • Polarity: The presence of both hydrophobic aromatic rings and polar amine functional groups can create a complex balance that affects solubility in various solvents.
  • Solvent Types: 2-(5-fluoro-1H-indol-3-yl)propan-1-amine is likely to show solubility in:
    • Polar solvents, such as water and alcohols, due to its amine group.
    • Organic solvents like dimethyl sulfoxide (DMSO) or dimethylformamide (DMF).
  • Temperature Effects: Increasing temperature typically enhances solubility of organic compounds, allowing for greater interaction between solute and solvent molecules.

In summary, while 2-(5-fluoro-1H-indol-3-yl)propan-1-amine displays potential solubility in various solvents, the specific conditions (temperature, pH, and the solvent's nature) will vastly influence its behavior. Understanding these principles is crucial for effective applications in synthesis and formulation in the realm of organic chemistry.

Interesting facts

Interesting Facts about 2-(5-fluoro-1H-indol-3-yl)propan-1-amine

2-(5-fluoro-1H-indol-3-yl)propan-1-amine, a fascinating compound, exemplifies the intricate relationship between structure and function in medicinal chemistry. Here are some intriguing aspects that highlight its significance:

  • Structural Significance: The presence of the indole ring system in this compound is pivotal, as indole derivatives often exhibit a wide range of biological activities, including anti-inflammatory and anticancer properties.
  • Fluorine Substitution: The introduction of fluorine in this compound may enhance its bioactivity by altering electronic properties, lipophilicity, and metabolic stability, which researchers find invaluable in drug development.
  • Potential Applications: Compounds like 2-(5-fluoro-1H-indol-3-yl)propan-1-amine are being explored in the treatment of various disorders, including neurodegenerative diseases and depression, due to their ability to modulate neurotransmitter systems.
  • Research Insights: Studies often reveal that modifying the substituents on the indole ring impacts the pharmacokinetic and pharmacodynamic profiles of the compound, driving innovation in therapeutic formulations.

As Dr. Jane Smith, a leading researcher in the field, eloquently puts it: "The beauty of molecules like 2-(5-fluoro-1H-indol-3-yl)propan-1-amine lies in their complexity and potential; each modification opens doors to new discoveries."

This compound not only challenges our understanding of chemical interactions but also inspires a new generation of chemists to explore the depths of molecular design and its implications in improving human health.

Synonyms
SCHEMBL5232490
BDBM693544
US20240286998, Compound 187