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5-Fluoro-AMT hydrochloride

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Identification
Molecular formula
C11H14ClFN2
CAS number
858951-06-1
IUPAC name
2-(5-fluoro-1H-indol-3-yl)propylammonium;chloride
State
State

In normal conditions and at room temperature, 5-Fluoro-AMT hydrochloride is a solid. It is common for compounds like this to be stored in a dry, cool place to maintain stability and prevent any decomposition or reaction with the environment.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.00
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
215.69g/mol
Molar mass
215.6800g/mol
Density
1.2560g/cm3
Appearence

5-Fluoro-AMT hydrochloride typically appears as an off-white to white crystalline powder. The crystalline structure can vary depending on the level of purity and the conditions under which the compound was crystallized.

Comment on solubility

Solubility of 2-(5-fluoro-1H-indol-3-yl)propylammonium chloride

2-(5-fluoro-1H-indol-3-yl)propylammonium chloride, with its unique structural features, showcases noteworthy solubility characteristics. As a quaternary ammonium compound, it is generally soluble in polar solvents, particularly water, due to the presence of the ammonium group which can interact favorably with water molecules.

Some key points about its solubility include:

  • Water Solubility: The ionic nature of the chloride salt enhances its solubility in water, making it suitable for various biological and chemical applications.
  • Solvent Dependence: While highly soluble in water, this compound may have varied solubility in organic solvents. For example, it might be less soluble in non-polar solvents due to its charged nature.
  • Temperature Influence: Thermal conditions can significantly affect solubility; typically, an increase in temperature enhances the solubility of ionic compounds.
  • pH Sensitivity: The solubility might also be impacted by the pH of the solution, as changes in acidity can affect the ionization of the ammonium group.

In summary, 2-(5-fluoro-1H-indol-3-yl)propylammonium chloride demonstrates favorable solubility characteristics in water, guided by its ionic nature and the influence of environmental conditions. Understanding these solubility properties is crucial for its effective utilization in research and applications.

Interesting facts

Interesting Facts about 2-(5-fluoro-1H-indol-3-yl)propylammonium Chloride

2-(5-fluoro-1H-indol-3-yl)propylammonium chloride is a fascinating compound that lies at the intersection of organic chemistry and medicinal research. This molecule, featuring a unique blend of an indole core and a propylammonium side chain, has garnered attention for several reasons:

  • Biological Interest: Indole derivatives are widely recognized for their diverse biological activities, including anti-cancer, anti-inflammatory, and neuroprotective properties. The incorporation of a fluorine atom in this compound may enhance its pharmacological profile by improving ligand binding and metabolic stability.
  • Applications in Neuroscience: Research has indicated that compounds with structural similarities to 2-(5-fluoro-1H-indol-3-yl)propylammonium chloride can act as modulators of serotonin receptors. This could potentially make it a candidate for treating mood disorders and anxiety.
  • Synthetic Versatility: The synthesis of indole-containing compounds, specifically through modifications of the indole ring, showcases the versatility of organic synthesis techniques. This allows chemists to tailor compounds for specific applications, enhancing their functionality.
  • Fluorine Chemistry: The presence of fluorine can impart unique chemical characteristics, such as increased lipophilicity and ionic interactions, which are crucial in drug design. This property can significantly influence the compound's behavior in biological systems.
  • Research Potential: Given its intriguing structure, ongoing investigations into the pharmacological potential of 2-(5-fluoro-1H-indol-3-yl)propylammonium chloride are important. Its study could unlock new therapeutic avenues, particularly in mental health.

In conclusion, the study of 2-(5-fluoro-1H-indol-3-yl)propylammonium chloride is a prime example of how modifications at the molecular level can lead to compounds with significant biological implications. As research progresses, this compound might contribute to critical advancements in drug discovery and development.

Synonyms
5-Fluoro-beta-methyltryptamine hydrochloride
3-(2-Amino-1-methylethyl)-5-fluoroindole hydrochloride
776-55-6
NSC 96938
Indole-3-ethylamine, 5-fluoro-beta-methyl-, hydrochloride
1H-Indole-3-ethanamine, 5-fluoro-beta-methyl-, hydrochloride
INDOLE, 3-(2-AMINO-1-METHYLETHYL)-5-FLUORO-, HYDROCHLORIDE