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2-(5-hydroxybenzothiophen-3-yl)acetic acid

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Identification
Molecular formula
C10H8O3S
CAS number
52172-29-7
IUPAC name
2-(5-hydroxybenzothiophen-3-yl)acetic acid
State
State

At room temperature, 2-(5-hydroxybenzothiophen-3-yl)acetic acid is in a solid state. It is stable under standard conditions, but like many organic compounds, it should be stored in a cool, dry, and well-ventilated place, away from sources of moisture and ignition.

Melting point (Celsius)
165.00
Melting point (Kelvin)
438.15
Boiling point (Celsius)
450.00
Boiling point (Kelvin)
723.15
General information
Molecular weight
208.25g/mol
Molar mass
208.2470g/mol
Density
1.4195g/cm3
Appearence

2-(5-hydroxybenzothiophen-3-yl)acetic acid typically appears as a crystalline solid. The color of the compound can range from white to light brown, depending on the level of purity and the presence of any impurities. It is generally odorless or may have a faint characteristic smell.

Comment on solubility

Solubility of 2-(5-hydroxybenzothiophen-3-yl)acetic acid

The solubility of 2-(5-hydroxybenzothiophen-3-yl)acetic acid can be explored through various factors, primarily influenced by its molecular structure and the presence of functional groups.

Factors Affecting Solubility

  • Hydrophilicity vs. Hydrophobicity: The presence of a hydroxyl group (-OH) typically enhances the compound's ability to interact with water, suggesting a degree of hydrophilicity.
  • pH Dependency: As an acid, the solubility may be influenced by the pH of the solution; it can become more soluble in basic environments where it may lose a hydrogen ion, leading to a more ionized form.
  • Temperature Influence: Solubility may also vary with temperature, often increasing with rising temperature for organic acids.

In practical terms, this compound may demonstrate moderate solubility in polar solvents like water, while potentially exhibiting higher solubility in organic solvents such as ethanol or acetone due to its aromatic character. The ability to form hydrogen bonds through its hydroxyl group enhances its solubility profile in various media.

In summary, the solubility of 2-(5-hydroxybenzothiophen-3-yl)acetic acid is a complex interplay of structural components and environmental conditions, making it a compound of interest for further exploration in different solvation contexts.

Interesting facts

Interesting Facts about 2-(5-hydroxybenzothiophen-3-yl)acetic acid

2-(5-hydroxybenzothiophen-3-yl)acetic acid is a fascinating chemical compound with unique properties and potential applications. Here are some intriguing aspects to consider:

  • Benzothiophene Backbone: The compound features a benzothiophene structure, which is known for its presence in various natural products and synthetic compounds. This particular framework contributes to the compound's distinct chemical behavior.
  • Hydroxyl Group Activity: The presence of a hydroxyl (–OH) group enhances the compound's reactivity, making it a potential candidate for diverse chemical reactions. Hydroxyl groups are often involved in hydrogen bonding, influencing solubility and boiling behavior.
  • Biological Relevance: Compounds related to benzothiophene have shown various biological activities, including anti-inflammatory and anti-cancer properties. This raises exciting research possibilities for 2-(5-hydroxybenzothiophen-3-yl)acetic acid in medicinal chemistry.
  • Versatile Applications: Given its unique structure, this compound can be explored in applications ranging from pharmaceuticals to agrochemicals. The potential for use in developing new therapeutic agents is particularly promising.
  • Research Implications: Ongoing studies may uncover further insights about this compound's mechanisms and interactions, possibly leading to novel discoveries in the realm of organic chemistry.

In conclusion, 2-(5-hydroxybenzothiophen-3-yl)acetic acid stands out not only for its complex structure but also for its potential applications in various scientific fields. Its exploration could yield significant benefits in advancing both basic and applied research.

Synonyms
16304-48-6
BRN 1373644
5-Hydroxybenzo(b)thiophene-3-acetic acid
BENZO(b)THIOPHENE-3-ACETIC ACID, 5-HYDROXY-
Benzo[b]thiophene-3-acetic acid, 5-hydroxy-
DTXSID20167503
DTXCID9089994
5-18-07-00363 (Beilstein Handbook Reference)