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5-Methoxy-N-methyl-N-isopropyltryptamine

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Identification
Molecular formula
C12H16N2O
CAS number
1019-45-0
IUPAC name
2-(5-methoxy-1H-indol-3-yl)propan-1-amine
State
State

At room temperature, it is a solid crystalline substance. Due to its crystalline nature, its appearance may vary slightly based on its purity and form.

Melting point (Celsius)
44.50
Melting point (Kelvin)
317.65
Boiling point (Celsius)
329.30
Boiling point (Kelvin)
602.45
General information
Molecular weight
204.28g/mol
Molar mass
204.2780g/mol
Density
1.2030g/cm3
Appearence

The compound is a crystalline solid that may appear in various shades of white to off-white. It is typically odorless and may be available in powdered form for laboratory uses.

Comment on solubility

Solubility of 2-(5-methoxy-1H-indol-3-yl)propan-1-amine

The solubility of 2-(5-methoxy-1H-indol-3-yl)propan-1-amine can be influenced by several factors including its chemical structure, the presence of functional groups, and the solvent used. As a compound featuring a methoxy group and an indole structure, it is important to consider the following:

  • Polar vs. Non-Polar Solvents: Due to the presence of the polar amine group, this compound is likely more soluble in polar solvents such as water or methanol compared to non-polar solvents. However, the methoxy group may also impart some hydrophobic character, complicating solubility in purely polar environments.
  • Hydrogen Bonding: The amine group can form hydrogen bonds with water molecules, enhancing its solubility in aqueous solutions. This highlights the effect of molecular interactions on solubility.
  • pH Sensitivity: The solubility can change with pH. In acidic conditions, the amine group may become protonated, which could increase its solubility in water significantly compared to neutral conditions.

In conclusion, while 2-(5-methoxy-1H-indol-3-yl)propan-1-amine exhibits potential solubility in polar solvents, the specific degree of solubility would require empirical testing in various conditions. Experimentation is key, as the interactions between the compound and the solvent greatly determine the final outcome of solubility.

Interesting facts

Exploring 2-(5-methoxy-1H-indol-3-yl)propan-1-amine

The compound known as 2-(5-methoxy-1H-indol-3-yl)propan-1-amine is a fascinating structure that belongs to the class of indole derivatives. It exhibits a unique combination of properties that make it subject to various scientific inquiries and applications.

Significant Features:

  • Structural Diversity: The indole framework is well-known in medicinal chemistry, often serving as a scaffold for a range of biologically active compounds.
  • Biological Potential: Compounds with such structures are being explored for their potential therapeutic effects, including anti-cancer and neuroprotective activities.
  • Synergistic Interactions: The presence of the methoxy group may enhance the compound's interactions within biological systems, leading to novel applications in pharmacology.
  • Research Interest: Due to its unique composition, this compound has caught the attention of researchers investigating serotonin receptors and their functions.

This compound also exemplifies the incredible complexity found within organic chemistry, demonstrating how simple variations in molecular structure can lead to significantly different properties and impacts. As with many indole derivatives, understanding its behavior in biochemical pathways may open up exciting avenues for future research.
"In chemistry, the simple can lead to the profound," one might say, and here, in the case of 2-(5-methoxy-1H-indol-3-yl)propan-1-amine, this statement rings particularly true.

Synonyms
5-Methoxy-beta-methyltryptamine
2-(5-methoxy-1H-indol-3-yl)propan-1-amine
20731-70-8
CHEMBL149564
BRN 0477184
INDOLE, 3-(3-AMINO-2-PROPYL)-5-METHOXY-
5-22-12-00091 (Beilstein Handbook Reference)
SCHEMBL9673757
DTXSID50942946
BDBM50068516
AKOS022505994
2-(5-Methoxy-1H-indol-3-yl)-propylamine
CS-0275392
EN300-6739696