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Identification
Molecular formula
C13H15NO2
CAS number
73-31-4
IUPAC name
2-[5-methoxy-2-methyl-1-(3-phenylprop-2-enoyl)indol-3-yl]acetic acid
State
State

At room temperature, the compound exists as a solid.

Melting point (Celsius)
116.50
Melting point (Kelvin)
389.65
Boiling point (Celsius)
586.10
Boiling point (Kelvin)
859.25
General information
Molecular weight
232.28g/mol
Molar mass
232.2790g/mol
Density
1.3300g/cm3
Appearence

The compound is typically a white to slightly off-white crystalline powder. It is slightly soluble in water and miscible in many organic solvents. The crystalline form may appear in a variety of crystal habits depending on the crystallization conditions.

Comment on solubility

Solubility of 2-[5-methoxy-2-methyl-1-(3-phenylprop-2-enoyl)indol-3-yl]acetic acid

The solubility of the compound 2-[5-methoxy-2-methyl-1-(3-phenylprop-2-enoyl)indol-3-yl]acetic acid is noteworthy and can be influenced by various factors:

  • Polarity: The presence of both hydrophilic and hydrophobic regions within the molecule will affect its solubility in different solvents. Generally, compounds with more polar functional groups tend to be more soluble in polar solvents like water.
  • pH Dependence: The solubility of acids can be impacted by the pH of the environment. In an acidic solution, the acid form is more prevalent, while increased pH may lead to the deprotonated form, altering its solubility characteristics.
  • Solvent Selection: This compound may show better solubility in organic solvents such as ethanol, methanol, or acetone, rather than in water, due to its complex structure and aromatic components.

In conclusion, while the precise solubility parameters for 2-[5-methoxy-2-methyl-1-(3-phenylprop-2-enoyl)indol-3-yl]acetic acid can depend on experimental conditions, understanding these influences can provide valuable insight into its behavior in different chemical environments. As always, conducting solubility tests under varying conditions is essential for a comprehensive evaluation.

Interesting facts

Interesting Facts about 2-[5-methoxy-2-methyl-1-(3-phenylprop-2-enoyl)indol-3-yl]acetic acid

This remarkable compound, known for its complex structure and potential applications, is derived from the indole family of compounds, which play a significant role in various biological activities.

Key Features

  • Indole Derivatives: This compound belongs to a class of compounds that are crucial in medicinal chemistry. Indole derivatives have been associated with a variety of pharmacological effects, including anti-cancer, anti-inflammatory, and antimicrobial properties.
  • Bioactivity: The presence of the methoxy and phenylprop-2-enoyl groups indicates a potential for significant biological activity, making it a subject of interest for drug development.
  • Structure-Activity Relationship: The unique structure of this compound allows chemists to explore how slight modifications can influence its activity. This opens up avenues for synthesizing analogs with enhanced efficacy.
  • Synthetic Pathways: The synthesis of such complex organic molecules typically involves multi-step reactions, showcasing the ingenuity of synthetic organic chemistry. Understanding these pathways can help students and researchers develop new methodologies.
  • Research Potential: Current research is focused on the exploration of its mechanisms in biological systems, which may lead to novel therapeutic agents and contribute to the understanding of various diseases.

"The beauty of organic chemistry lies in the subtle dance of atoms and the profound effects that slight changes can have on the properties of a compound."

In summary, 2-[5-methoxy-2-methyl-1-(3-phenylprop-2-enoyl)indol-3-yl]acetic acid stands as a fascinating example of how intricate chemical structures can lead to significant discoveries in medicine. Its active components and diverse applications continue to inspire researchers in the field.

Synonyms
SCHEMBL25139
NS00050126
1H-Indole-3-acetic acid, 5-methoxy-2-methyl-1-(1-oxo-3-phenyl-2-propen-1-yl)-