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5-Methoxy-6-methyl-2-aminoindan

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Identification
Molecular formula
C12H15NO2
CAS number
null
IUPAC name
2-(5-methoxy-2-methyl-benzofuran-3-yl)ethanamine
State
State

At room temperature, 5-Methoxy-6-methyl-2-aminoindan is in a solid state. It is often encountered as a powder and is not known to evaporate. Being a solid, it is generally stable under standard conditions of temperature and pressure if stored properly.

Melting point (Celsius)
147.00
Melting point (Kelvin)
420.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
191.24g/mol
Molar mass
191.2410g/mol
Density
1.2160g/cm3
Appearence

5-Methoxy-6-methyl-2-aminoindan is a white or off-white crystalline powder. It is typically available in its hydrochloride salt form, which enhances its stability and solubility in water. The compound is sensitive to air and light, and should be stored in a cool, dry place to preserve its integrity.

Comment on solubility

Solubility of 2-(5-methoxy-2-methyl-benzofuran-3-yl)ethanamine

The solubility of 2-(5-methoxy-2-methyl-benzofuran-3-yl)ethanamine is an intriguing topic, as it encompasses various aspects that influence its behavior in different solvents. Understanding its solubility can help inform applications in pharmaceuticals and other chemical industries. Here are some key points:

  • Polar vs. Nonpolar Solvents: Solubility is often governed by the principle of "like dissolves like." This compound, with its aromatic structure and functional groups, may exhibit better solubility in polar organic solvents such as methanol and ethanol compared to nonpolar solvents like hexane.
  • Temperature Effects: An increase in temperature can enhance the solubility of many organic compounds, including this one. This is particularly important when considering its applications at varying temperatures.
  • pH Influence: The solubility can also be affected by the pH of the solution. Changes in pH may lead to protonation or deprotonation of the amine group, thereby influencing the overall solubility in aqueous environments.
  • Hydrogen bonding: The presence of the methoxy group may introduce opportunities for hydrogen bonding, which can further affect solubility dynamics with polar solvents.

In conclusion, the solubility of 2-(5-methoxy-2-methyl-benzofuran-3-yl)ethanamine is multifaceted, influenced by a variety of factors including solvent type, temperature, pH, and intermolecular interactions. Understanding these principles is essential for optimizing its usage in various chemical applications.

Interesting facts

Interesting Facts about 2-(5-Methoxy-2-methyl-benzofuran-3-yl)ethanamine

The compound 2-(5-methoxy-2-methyl-benzofuran-3-yl)ethanamine, often referred to in the context of synthetic chemistry and psychoactive research, exhibits unique structural characteristics and potential implications in various fields. Here are several engaging points about this intriguing compound:

  • Structural Uniqueness: The presence of the benzofuran moiety combined with ethanamine creates a fascinating framework that can influence its reactivity and biological activity.
  • Potential Biological Activity: Compounds sharing similar structures have shown potential in neuropharmacology, making this compound an interesting candidate for further research in mental health therapies.
  • Synthetic Pathways: The synthesis of compounds like 2-(5-methoxy-2-methyl-benzofuran-3-yl)ethanamine can involve various synthetic routes, highlighting the creativity and complexity in organic synthesis.
  • Research Interest: Due to its structural properties, it has garnered attention in studies looking at novel psychoactive substances, drawing interest from both chemists and pharmacologists.
  • Versatility: The methoxy and methyl substitutions modify the compound's activity, indicating a relationship between molecular structure and function that can be finely tuned for targeted applications.

As the field of medicinal chemistry evolves, compounds like 2-(5-methoxy-2-methyl-benzofuran-3-yl)ethanamine stand at the intriguing intersection of chemical structure and potential therapeutic benefits. Scientists often reflect on the challenge of understanding how alterations at the molecular level can translate to significant changes in biological outcomes. As one scientist aptly puts it, “The power of chemistry lies in its ability to unlock the mysteries of nature.”


Ongoing research not only expands our understanding of this compound but also paves the way for future innovations in drug development and therapeutic interventions.

Synonyms
SCHEMBL9119624
2-methyl-3-aminoethyl-5-methoxybenzofuran