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5-MeO-BFE

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Identification
Molecular formula
C11H13NO2
CAS number
92494-38-7
IUPAC name
2-(5-methoxybenzofuran-6-yl)ethanamine
State
State

At room temperature, 5-MeO-BFE is typically a solid. This state is due to its melting point being significantly higher than room temperature, allowing it to maintain its structural integrity as a crystalline powder under standard atmospheric conditions.

Melting point (Celsius)
78.00
Melting point (Kelvin)
351.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
191.23g/mol
Molar mass
191.2300g/mol
Density
1.2140g/cm3
Appearence

5-MeO-BFE is typically found as a white to off-white crystalline powder. The appearance of this chemical is largely consistent with many synthetic compounds in its class, often possessing a fine texture that may clump due to electrostatic forces or slight moisture absorption.

Comment on solubility

Solubility of 2-(5-methoxybenzofuran-6-yl)ethanamine

The solubility of 2-(5-methoxybenzofuran-6-yl)ethanamine in various solvents can be quite intriguing. Several factors influence the solubility of this compound:

  • Polarity: Given that this compound contains both aromatic and aliphatic structures, its polarity will play a crucial role in its solubility. Typically, non-polar solvents such as hexane may show lower solubility, while polar solvents, like methanol or ethanol, could enhance dissolution.
  • Hydrogen bonding: The presence of an amine group in this compound suggests the potential for hydrogen bonding with polar solvents, which can significantly increase solubility.
  • Temperature: As with many organic compounds, solubility often increases with temperature. Therefore, heating the solvent might be beneficial for achieving better solubilization.
  • pH level: The solubility of the amine can be affected by the pH of the solution, where low pH (acidic conditions) may lead to protonation of the amine group, enhancing solubility in water.

In general, compounds similar to 2-(5-methoxybenzofuran-6-yl)ethanamine tend to be sparingly soluble in water but may find better solubility in organic solvents. It is essential to conduct empirical tests to determine the specific solubility characteristics under various conditions for practical applications.

Interesting facts

Exploring 2-(5-Methoxybenzofuran-6-yl)ethanamine

2-(5-Methoxybenzofuran-6-yl)ethanamine, a fascinating compound, is part of a larger family known as benzofurans. These compounds have unique structural features that allow them to participate in various chemical reactions and display a wide range of biological activities. Here are some intriguing facts about this compound:

  • Structures and Activity: The presence of the benzofuran moiety is significant, as it often contributes to the pharmacological activity of compounds. Benzofurans are known for their potential use in antidepressants, antipsychotics, and anti-inflammatory agents.
  • Role in Research: This compound may serve as a *lead compound* in the development of new drugs, particularly in the realms of neuroscience and psychiatry. Its structure can be modified to explore different biological activities.
  • Synthesis Routes: The synthesis of 2-(5-methoxybenzofuran-6-yl)ethanamine can be challenging, involving multiple steps and the need for precise control of reaction conditions. This often piques the interest of synthetic chemists.
  • Natural Compounds: Benzofurans are often found in nature, particularly in plants, leading to investigations into their antioxidant and medicinal properties, enhancing their appeal in both chemistry and pharmacology.
  • Influence on Mood: Some studies suggest that compounds like 2-(5-methoxybenzofuran-6-yl)ethanamine could influence the serotonin system, potentially affecting mood and emotional responses.

In summary, 2-(5-methoxybenzofuran-6-yl)ethanamine encapsulates a beautiful convergence of synthetic chemistry, natural product isolation, and medicinal applications. As research in this area continues to expand, we may uncover even more about its potential benefits and applications, making it an exciting topic of exploration!

Synonyms
5-Methoxy-6-benzofuranethylamine
627J14PO9P
6-Benzofuranethanamine, 5-methoxy-
6-Benzofuranethylamine, 5-methoxy-
UNII-627J14PO9P
27892-40-6
Q27263458