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Celecoxib

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Identification
Molecular formula
C17H14N2O
CAS number
169590-42-5
IUPAC name
2-(5-methyl-2-phenyl-pyrazol-3-yl)oxyethanol
State
State

At room temperature, celecoxib is a solid.

Melting point (Celsius)
157.00
Melting point (Kelvin)
430.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
381.37g/mol
Molar mass
381.3720g/mol
Density
1.0000g/cm3
Appearence

Celecoxib appears as a crystalline solid with a white to off-white color.

Comment on solubility

Solubility of 2-(5-methyl-2-phenyl-pyrazol-3-yl)oxyethanol

The solubility of 2-(5-methyl-2-phenyl-pyrazol-3-yl)oxyethanol can be influenced by various factors, including its molecular structure and the polarities of the solvents involved. This compound presents some intriguing solubility characteristics:

  • Polar solvents: Due to the presence of the hydroxyl group (-OH), this compound is more likely to be soluble in polar solvents like water, as the -OH group can form hydrogen bonds.
  • Nonpolar solvents: Conversely, it may exhibit lower solubility in nonpolar solvents because of its polar functional groups, which tend to favor interactions with polar environments.
  • Temperature effect: Increasing the temperature may also affect solubility, often resulting in greater solubility for many organic compounds.
  • Concentration of solute: The concentration of the substance in the solvent can lead to saturation, limiting the solubility as more solute is added.

In summary, understanding the solubility of 2-(5-methyl-2-phenyl-pyrazol-3-yl)oxyethanol is intricate and multifaceted. Its ability to dissolve effectively hinges on both the chemical interactions at play and the choice of solvent. As the saying goes, “Like dissolves like,” thus highlighting the importance of matching polarities for optimal solubility outcomes.

Interesting facts

Interesting Facts about 2-(5-Methyl-2-phenyl-pyrazol-3-yl)oxyethanol

2-(5-Methyl-2-phenyl-pyrazol-3-yl)oxyethanol, a compound featuring a unique pyrazole moiety, has been a topic of interest in various research fields, particularly in medicinal chemistry. Here are some intriguing aspects of this compound:

  • Versatile Applications: Compounds containing pyrazole rings are known for their diverse biological activities, including anti-inflammatory, antioxidant, and antimicrobial properties. This makes 2-(5-methyl-2-phenyl-pyrazol-3-yl)oxyethanol a candidate for further exploration in drug development.
  • Chemical Structure: The structure incorporates both a pyrazole and an ether link, which can influence its reactivity and stability. The presence of the aromatic phenyl group enhances the compound's potential as a pharmacophore.
  • Research Potential: Ongoing studies are examining the compound's efficacy in treating various diseases. Its unique structure raises questions about its interactions on a molecular level.
  • Synergistic Effects: The combination of the pyrazole and ether functionalities can lead to synergistic effects in therapeutic applications, making it a fascinating subject for pharmacological research.
  • Environmental Studies: Due to the ether component, researchers are also looking into the compound's behavior in environmental settings, assessing its possible roles in ecosystem interactions.

As scientists and students delve into the world of 2-(5-methyl-2-phenyl-pyrazol-3-yl)oxyethanol, they are uncovering not just its chemical properties but also its significant potential in improving health outcomes and contributing to environmental chemistry. Each study uncovers layers of information that could lead to groundbreaking discoveries!

Synonyms
BRN 0195184
5372-10-1
P-311
ETHANOL, 2-(3-METHYL-1-PHENYL-5-PYRAZOLYLOXY)-
2-(3-Methyl-1-phenyl-5-pyrazolyloxy)ethanol
DTXSID70201981
5-(2-Hydroxyethoxy)-3-methyl-1-phenylpyrazole
0-23-00-00355 (Beilstein Handbook Reference)
DTXCID00124472