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Trimetazidine hydrochloride

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Identification
Molecular formula
C14H24ClN3O3
CAS number
13171-25-0
IUPAC name
2-[(5-methylpyridin-1-ium-2-yl)amino]-1-phenyl-ethanol;chloride
State
State

The compound is in a solid state at room temperature, typically forming crystalline structures.

Melting point (Celsius)
213.00
Melting point (Kelvin)
486.15
Boiling point (Celsius)
465.50
Boiling point (Kelvin)
738.65
General information
Molecular weight
291.81g/mol
Molar mass
291.8080g/mol
Density
1.0115g/cm3
Appearence

Trimetazidine hydrochloride appears as a white to almost white crystalline powder. It is hygroscopic in nature and can readily absorb moisture from the environment.

Comment on solubility

Solubility of 2-[(5-methylpyridin-1-ium-2-yl)amino]-1-phenyl-ethanol;chloride

The solubility of 2-[(5-methylpyridin-1-ium-2-yl)amino]-1-phenyl-ethanol;chloride can be influenced by various factors, notably the presence of the pyridinium ion, which plays a crucial role in its interaction with solvents.

  • Polar Solvents: This compound is expected to exhibit good solubility in polar solvents due to its ionic nature.
  • Aqueous Solution: As a chloride salt, it is likely to be soluble in water, allowing it to dissociate into its constituent ions.
  • Non-Polar Solvents: Its solubility in non-polar solvents is anticipated to be limited because of the polar functional groups present in its structure.

To summarize, "the solubility properties of this compound can be highly dependent on the solvent choice." It's critical to consider environmental factors such as temperature and pH, which may further influence its solubility profile.


Interesting facts

Interesting Facts About 2-[(5-Methylpyridin-1-ium-2-yl)amino]-1-phenyl-ethanol; Chloride

This compound is a fascinating example of a quaternary ammonium salt, illustrating the rich chemistry of nitrogen-containing molecules. Here are some intriguing aspects:

  • Dual Functionality: The presence of both a phenyl group and a pyridin-ium structure allows this compound to exhibit diverse chemical behavior, making it valuable in various organic synthesis reactions.
  • Biological Relevance: Compounds containing pyridine moieties are widely recognized for their biological activity. They potentially serve as intermediates or precursors in pharmaceuticals, particularly due to their ability to participate in hydrogen bonding.
  • Research Applications: This compound finds applications in research areas such as medicinal chemistry and materials science, where investigating the interactions of aromatic systems is crucial.
  • Electrochemical Properties: The charged nature of the quaternary ammonium cation may exhibit interesting electrochemical properties, offering opportunities in areas like electrochemistry and battery research.

In the world of synthetic organic chemistry, compounds like 2-[(5-methylpyridin-1-ium-2-yl)amino]-1-phenyl-ethanol; chloride serve not only as building blocks in synthesis but also as models for studying the behavior of more complex molecules.

As researchers continue to explore the properties and applications of such compounds, it becomes apparent that understanding their chemistry can unveil new avenues for innovation in both technology and medicine.

Synonyms
alpha-((5-Methyl-2-pyridylamino)methyl)benzyl alcohol hydrochloride
BENZYL ALCOHOL, alpha-((5-METHYL-2-PYRIDYLAMINO)METHYL)-, HYDROCHLORIDE
1085-14-9