Skip to main content

Nitrofurazone

ADVERTISEMENT
Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
2-[(5-nitro-2-furyl)methyleneamino]guanidine
State
State

At room temperature, nitrofurazone is found in a solid state, typically as a powder.

Melting point (Celsius)
236.00
Melting point (Kelvin)
509.00
Boiling point (Celsius)
258.00
Boiling point (Kelvin)
531.00
General information
Molecular weight
198.14g/mol
Molar mass
198.1550g/mol
Density
1.7600g/cm3
Appearence

Nitrofurazone typically appears as a yellow, crystalline powder. It is quite bright in color and can appear luminous under certain lighting conditions due to its crystalline structure.

Comment on solubility

Solubility of 2-[(5-nitro-2-furyl)methyleneamino]guanidine

The compound 2-[(5-nitro-2-furyl)methyleneamino]guanidine exhibits intriguing solubility characteristics that can be influenced by several factors. Understanding its solubility is key for various applications in both medicinal and industrial chemistry.

Key Factors Influencing Solubility

  • Polarity: The presence of nitro and furyl groups contributes to the polarity of the molecule, affecting its ability to dissolve in polar solvents.
  • Hydrogen Bonding: With the guanidine functional group, this compound may engage in hydrogen bonding, enhancing its solubility in solvents capable of participating in such interactions.
  • pH Level: The solubility may vary with pH; this compound could be more soluble at certain pH levels due to protonation/deprotonation of functional groups.

It is noteworthy that solubility can also vary with temperature and the type of solvent used. In general, compounds like 2-[(5-nitro-2-furyl)methyleneamino]guanidine might find higher solubility in organic solvents compared to water, but this can be further evaluated through empirical testing.

As a takeaway, one might quote, “Understanding the solubility profile of such compounds is crucial for optimizing their applications in various domains” emphasizing the importance of solubility in chemical research.

Interesting facts

Interesting Facts about 2-[(5-nitro-2-furyl)methyleneamino]guanidine

The compound 2-[(5-nitro-2-furyl)methyleneamino]guanidine is an intriguing molecule that has garnered attention in various fields of research due to its unique structural features and potential applications. Here are some noteworthy aspects:

  • Biological Activity: This compound is known for its potential biological properties, particularly as an antimicrobial agent. Its structural moiety, the 5-nitro-2-furyl group, is linked to a variety of biological activities, making this compound a subject of study in medicinal chemistry.
  • Synthetic Versatility: The synthetic pathways leading to 2-[(5-nitro-2-furyl)methyleneamino]guanidine often involve condensation reactions, which can be adapted to introduce various substituents—allowing for the exploration of structure-activity relationships.
  • Research Potential: It has been investigated for its utility in developing new therapies for bacterial infections. The unique nitro-furyl moiety presents opportunities for research into new antibiotic compounds.
  • Environmental Impact: Furyl derivatives are prevalent in nature, but compounds like this one may also have implications for environmental chemistry, particularly when exploring the degradation of harmful materials.
  • Historical Context: Nitro-containing compounds have a rich history in chemistry; the introduction of the nitro group has been linked to both enhancement and modification of biological activity in a variety of compounds.

In conclusion, 2-[(5-nitro-2-furyl)methyleneamino]guanidine stands as a compelling example of how a single compound can bridge multiple scientific disciplines, including pharmacology, environmental science, and synthetic chemistry. As research continues, it may reveal even more captivating applications and implications!

Synonyms
5-Nitrofurfurylidenaminoguanidin
AKOS017264668