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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
2-[(5-nitro-2-furyl)methyleneamino]guanidine;hydrochloride
State
State

Nitrofurazone is typically found in a solid state at room temperature. Its solid-state physical form is essential for its application in various pharmaceutical formulations.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.15
Boiling point (Celsius)
222.00
Boiling point (Kelvin)
495.15
General information
Molecular weight
198.16g/mol
Molar mass
198.1550g/mol
Density
1.5809g/cm3
Appearence

Nitrofurazone appears as a yellow crystalline powder. This vibrant color is a characteristic feature, and it typically presents in the form of fine crystalline needles.

Comment on solubility

Solubility of 2-[(5-nitro-2-furyl)methyleneamino]guanidine; hydrochloride

The solubility of 2-[(5-nitro-2-furyl)methyleneamino]guanidine; hydrochloride is influenced by various factors that are important to consider:

  • Polarity: This compound contains both polar and non-polar regions due to its furan and guanidine moieties, which affects how it interacts with solvents.
  • Solvent Choice: It is likely to be more soluble in polar solvents, particularly water and alcohols due to the presence of the hydrochloride group.
  • Temperature: Increased temperature can often enhance solubility, making it worthwhile to explore varying conditions when dissolving this compound.
  • pH Level: As a hydrochloride salt, alterations in pH could impact the solubility as well; it may become more soluble in acidic conditions.

In summary, while specific solubility data may not be widely reported for this compound, understanding the factors that influence solubility is crucial for researchers aiming to utilize this substance effectively in various applications. Therefore, experimenting with different solvents and conditions may yield the best results for solubilizing 2-[(5-nitro-2-furyl)methyleneamino]guanidine; hydrochloride.

Interesting facts

Interesting Facts about 2-[(5-nitro-2-furyl)methyleneamino]guanidine Hydrochloride

The compound 2-[(5-nitro-2-furyl)methyleneamino]guanidine hydrochloride is a fascinating example of an organic compound that has garnered attention due to its potential applications in various fields. Here are some interesting facts about this compound:

  • Pharmaceutical Potential: This compound has been studied for its potential roles as an anti-cancer agent, showcasing the importance of nitro-furyl derivatives in medicinal chemistry.
  • Mechanism of Action: The presence of the nitro group in its structure may contribute to its biological activity through mechanisms involving reactive nitrogen species, making it a subject of interest in the study of oxidative stress.
  • Importance of Guanidine: Guanidine derivatives are known for their diverse biological activities. They play critical roles in pharmaceuticals and biochemistry, highlighting the significance of this functional group.
  • Chemical Versatility: The ability of this compound to form stable complexes with metals may also offer potential uses in catalysis and material science, showcasing its versatility in chemical applications.
  • Research Opportunities: As researchers explore its properties further, this compound represents a valuable opportunity for the development of novel therapeutic agents.

With its unique structure and promising applications, 2-[(5-nitro-2-furyl)methyleneamino]guanidine hydrochloride exemplifies the intricate relationship between chemical structure and biological function, making it a compelling subject for study in modern chemistry.

Synonyms
2-((5-Nitrofuran-2-yl)methylene)hydrazinecarboximidamide hydrochloride
SB61215
DB-057516
N-{[(5-NITROFURAN-2-YL)METHYLIDENE]AMINO}GUANIDINE HYDROCHLORIDE