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Dosulepin

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Identification
Molecular formula
C19H21NS
CAS number
113-53-1
IUPAC name
2-(5,6-dihydrobenzo[b][1]benzothiepin-5-yloxy)-N,N-dimethyl-ethanamine
State
State

At room temperature, Dosulepin exists as a solid.

Melting point (Celsius)
136.00
Melting point (Kelvin)
409.15
Boiling point (Celsius)
465.00
Boiling point (Kelvin)
738.15
General information
Molecular weight
295.45g/mol
Molar mass
0.0000g/mol
Density
1.2000g/cm3
Appearence

Dosulepin typically appears as white or almost white crystalline powder. It is generally supplied in tablet form for medicinal use.

Comment on solubility

Solubility of 2-(5,6-dihydrobenzo[b][1]benzothiepin-5-yloxy)-N,N-dimethyl-ethanamine

The solubility of 2-(5,6-dihydrobenzo[b][1]benzothiepin-5-yloxy)-N,N-dimethyl-ethanamine is influenced by several factors due to its complex structure. Here are some key points regarding its solubility:

  • Polarity: The compound contains both hydrophobic (the benzothiepin moiety) and hydrophilic (the amine group) components, indicating that its solubility may vary significantly in different solvents.
  • Solvent Interaction: It is expected to have higher solubility in organic solvents such as ethanol and dichloromethane compared to water, owing to the bulky non-polar regions.
  • Temperature Dependency: Like many organic compounds, its solubility could improve with increased temperature, which often enhances molecular motion and interaction with solvent molecules.
  • pH Influence: The solubility might also be affected by the pH of the solution; with changes in pH, the amine group could become protonated, potentially increasing solubility in polar solvents.
  • Crystallinity: The structural rigidity from the fused ring systems may lead to crystal formation, thus impacting the overall solubility due to differences in dissolution rates.

In summary, the solubility of 2-(5,6-dihydrobenzo[b][1]benzothiepin-5-yloxy)-N,N-dimethyl-ethanamine can therefore be characterized as moderate and significantly variable depending on the solvent, temperature, pH, and physical state of the compound.

Interesting facts

Interesting Facts about 2-(5,6-dihydrobenzo[b][1]benzothiepin-5-yloxy)-N,N-dimethyl-ethanamine

2-(5,6-dihydrobenzo[b][1]benzothiepin-5-yloxy)-N,N-dimethyl-ethanamine is a fascinating compound with potential implications in pharmacology and materials science. Here are some intriguing aspects:

  • Structural Complexity: This compound features a unique structure that intertwines both a benzothiepin moiety and an amine functional group, indicating its possible utility in medicinal chemistry.
  • Pharmacological Potential: Compounds with similar structures often exhibit various biological activities, including anti-inflammatory, analgesic, and neuroprotective properties.
  • Mechanism of Action: The presence of the dimethylamine group suggests ways in which this compound can interact with neurotransmitter systems, possibly influencing serotonin or dopamine pathways.
  • Versatility in Synthesis: The synthetic pathways to create this compound are of interest to chemists. Reactions involving thiophene derivatives can lead to diverse functionalization opportunities, which can be explored for drug development.
  • Research Applications: This compound could serve as a valuable starting point for the development of new therapeutic agents aimed at treating neurological disorders or as a scaffold in the design of more complex molecules.

As research progresses, the exploration of 2-(5,6-dihydrobenzo[b][1]benzothiepin-5-yloxy)-N,N-dimethyl-ethanamine will undoubtedly uncover even more fascinating properties and applications, underscoring the importance of chemical diversity in drug discovery.

Synonyms
BRN 1292693
2-((10,11-Dihydrodibenzo(b,f)thiepin-10-yl)oxy)-N,N-dimethylethylamine
1527-21-5
5-17-04-00515 (Beilstein Handbook Reference)
ETHYLAMINE, 2-((10,11-DIHYDRODIBENZO(b,f)THIEPIN-10-YL)OXY)-N,N-DIMETHYL-
DTXSID80934576
AKOS005065525
2-[(10,11-Dihydrodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethan-1-amine