Skip to main content

Tolfenpyrad

ADVERTISEMENT
Identification
Molecular formula
C14H8F3N5
CAS number
129558-76-5
IUPAC name
2-(5H-tetrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]aniline
State
State

At room temperature, Tolfenpyrad is primarily found in a solid state, taking the form of a powder.

Melting point (Celsius)
156.30
Melting point (Kelvin)
429.45
Boiling point (Celsius)
510.80
Boiling point (Kelvin)
783.95
General information
Molecular weight
327.27g/mol
Molar mass
327.2680g/mol
Density
1.4900g/cm3
Appearence

Tolfenpyrad is a crystalline solid that can appear as a white to pale yellow powder. The specific shade may vary depending on the degree of purity and the presence of different polymorphs.

Comment on solubility

Solubility of 2-(5H-tetrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]aniline

The solubility of 2-(5H-tetrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]aniline can be quite intriguing, primarily due to its complex structure which includes both polar and non-polar components. Here are some points to consider:

  • Polar Characteristics: The presence of the tetrazole moiety enhances the polar character of the compound, potentially increasing its solubility in polar solvents such as water and alcohols.
  • Non-Polar Traits: Conversely, the trifluoromethyl group tends to make the compound more hydrophobic, which may limit its solubility in aqueous environments.
  • Combination Effects: The juxtaposition of polar and non-polar regions suggests that this compound may exhibit moderate solubility profiles, depending on the solvent used.
  • Solvent Choice: Non-polar solvents like dichloromethane or chloroform may hold better solubility for this compound compared to water, due to the influences of the trifluoromethyl group.

In summary, the overall solubility of 2-(5H-tetrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]aniline can be described as complex and variable, making empirical testing essential to determine its exact solubility in various solvents.

Interesting facts

Interesting Facts about 2-(5H-tetrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]aniline

This compound, 2-(5H-tetrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]aniline, is a fascinating example of a versatile organic compound that has drawn interest in various fields of research and application. One of the remarkable features of this compound is its incorporation of the tetrazole ring system, which is known for its biological activity and has been utilized in pharmaceuticals for its potential in drug discovery.

Here are some key points about this interesting compound:

  • Tetrazole Rings: The tetrazole moiety is not just a structural feature; it significantly enhances the compound's polar and non-polar attributes, facilitating a diverse range of interactions in biological systems.
  • Fluorinated Phenyl Group: The presence of the trifluoromethyl group on the phenyl ring is noteworthy. This group can increase the lipophilicity of the compound, often resulting in improved cellular permeability.
  • Research Applications: Compounds similar to this one have demonstrated interesting pharmacological properties, including anti-inflammatory and analgesic activities, making them attractive candidates for further study.
  • Synthetic Pathways: The synthesis of this compound involves multiple steps, including the synthesis of the tetrazole and the introduction of the trifluoromethyl group, showcasing the intricate methods of organic chemistry.

Moreover, this compound serves as a prime example of how organic chemists can design and modify molecules for specific purposes. As stated by one researcher, "The careful crafting of molecules at the atomic level opens up pathways for innovation in drug development."

The blend of reactivity, biological potential, and synthetic complexity makes 2-(5H-tetrazol-5-yl)-N-[3-(trifluoromethyl)phenyl]aniline a compound worthy of exploration in both academic and industrial fields.