Skip to main content

Nelarabine

ADVERTISEMENT
Identification
Molecular formula
C11H15N5O5
CAS number
121032-29-9
IUPAC name
2-[6-(2-furylmethylamino)purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
State
State
Nelarabine is typically in a solid crystalline form at room temperature.
Melting point (Celsius)
217.00
Melting point (Kelvin)
490.15
Boiling point (Celsius)
697.80
Boiling point (Kelvin)
970.95
General information
Molecular weight
297.27g/mol
Molar mass
297.2670g/mol
Density
1.6704g/cm3
Appearence
Nelarabine appears as a white to off-white crystalline powder.
Comment on solubility

Solubility of 2-[6-(2-furylmethylamino)purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

The solubility of the compound with the formula C11H15N5O5, formally known as 2-[6-(2-furylmethylamino)purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol, can be summarized as follows:

  • Solvent Interaction: This compound is likely to demonstrate varied solubility characteristics depending on the solvent used. Polar solvents such as water may provide better solubility due to the presence of hydroxyl (–OH) and amino (–NH) groups that can engage in hydrogen bonding.
  • Hydrophobic Elements: The furylmethyl and purinyl structures introduce some hydrophobic characteristics, possibly leading to decreased solubility in nonpolar solvents.
  • pH Dependence: Solubility may also be pH-dependent, influenced by the presence of ionizable groups which could behave differently under varying pH conditions.

In summary, the solubility of this compound is a complex interplay of its chemical structure and the nature of the solvent used. It is essential to conduct specific solubility tests in different solvents to fully characterize this compound's solubility profile. As the saying goes, "Like dissolves like," making understanding these interactions crucial in predicting solubility outcomes.

Interesting facts

Interesting Facts About 2-[6-(2-furylmethylamino)purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

This fascinating compound is a hybrid of purine and carbohydrate moieties, showcasing the intricate designs that nature employs in biochemical systems. Its complex structure allows it to interact effectively with biological systems, which leads to several significant implications.

Key Characteristics:

  • Biological Activity: The compound shares structural similarities with nucleotides, potentially influencing nucleic acid metabolism.
  • Enzyme Inhibition: It may serve as an inhibitor for critical enzymes, impacting various metabolic pathways and presenting opportunities for pharmaceutical advancements.
  • Research Applications: Scientists are exploring its properties for therapeutic use, particularly in cancer treatment and metabolic disorders.
  • Structural Diversity: The presence of both a purine base and a tetrahydrofuran ring showcases the compound’s versatility, contributing to its bioactivity and solubility profiles.

As researchers delve into the biochemical roles of this compound, it raises exciting questions about how molecular structure influences function. As famously stated, "The structure of a compound is the key to unlocking its potential."

Overall, 2-[6-(2-furylmethylamino)purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol stands as a testament to the profound relationship between molecular architecture and biological activity, making it a subject of interest in contemporary chemical and medicinal research.

Synonyms
Furfuryladenosine
Riboside, kinetin
6-Furfuryladenosine
Kinetin ribonucleoside
ADENOSINE, N-FURFURYL-
MLS002707095
Ribosylkinetin
Adenosine, N-(2-furanylmethyl)-
NSC 120958
CHEMBL18115
SCHEMBL217034
(2R,3R,4S,5R)-2-(6-(furan-2-ylmethylamino)-9H-purin-9-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol
BCP34390
NSC120958
AKOS003382320
NSC-120958
NCGC00094928-01
NCGC00094928-02
SMR001574490
NS00046394
N6-Furfuryladenosine;6-Furfurylaminopurine riboside;Ribosylkinetin
2-(6-(furan-2-ylmethylamino) purin-9-yl)-5-(hydroxymethyl) oxolane-3,4-diol
2-{6-[(2-furylmethyl)amino]-9H-purin-9-yl}-5-(hydroxymethyl)tetrahydrofuran-3,4-diol