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NADPH

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Identification
Molecular formula
C21H29N7O17P3S
CAS number
53-57-6
IUPAC name
[2-(6-aminopurin-9-yl)-5-[[[[3,4-dihydroxy-5-[3-(sulfanylcarbonimidoyl)pyridin-1-ium-1-yl]tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-tetrahydrofuran-3-yl] hydrogen phosphate
State
State

NADPH is generally found in a solid state at room temperature. It usually takes the form of a fine powder or crystalline structure, which should be handled with care to prevent degradation due to its sensitivity to light and oxygen.

Melting point (Celsius)
160.00
Melting point (Kelvin)
433.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
744.42g/mol
Molar mass
744.4190g/mol
Density
0.9990g/cm3
Appearence

NADPH appears as a white to off-white powder. It is typically odorless and stable under normal conditions. Due to its hygroscopic nature, it should be stored in a dry environment to prevent moisture absorption.

Comment on solubility

Solubility of 2-(6-aminopurin-9-yl)-5-[[[[3,4-dihydroxy-5-[3-(sulfanylcarbonimidoyl)pyridin-1-ium-1-yl]tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-tetrahydrofuran-3-yl] hydrogen phosphate (C21H29N7O17P3S)

The solubility of a compound like 2-(6-aminopurin-9-yl)-5-[[[[3,4-dihydroxy-5-[3-(sulfanylcarbonimidoyl)pyridin-1-ium-1-yl]tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-tetrahydrofuran-3-yl] hydrogen phosphate can often be influenced by several factors:

  • Polarity: Due to its diverse functional groups, the compound exhibits a range of polar characteristics, which might enhance its solubility in polar solvents such as water.
  • Hydrogen Bonding: The presence of multiple hydroxyl (–OH) groups suggests the potential for strong hydrogen bonding with solvent molecules.
  • Ionic Nature: The phosphate groups in the structure can contribute to its ability to dissolve in aqueous environments, particularly with the presence of ions.

In general, the solubility of complex compounds like this is best understood in terms of similarities in chemical structure. A common saying in chemistry is "like dissolves like." Therefore, exploring solubility in relation to solvents' properties is crucial:

  • Highly polar solvents: Likely to show good solubility due to potential interactions.
  • Non-polar solvents: Expected to have minimal or no solubility owing to unfavorable interactions.

Ultimately, experimental data is essential for determining the precise solubility characteristics of this compound, as predictions based solely on structure may not capture all nuances involved.

Interesting facts

Interesting Facts about 2-(6-aminopurin-9-yl)-5-[[[[3,4-dihydroxy-5-[3-(sulfanylcarbonimidoyl)pyridin-1-ium-1-yl]tetrahydrofuran-2-yl]methoxy-oxido-phosphoryl]oxy-hydroxy-phosphoryl]oxymethyl]-4-hydroxy-tetrahydrofuran-3-yl] hydrogen phosphate

This compound, a fascinating member of the phosphate family, broadens our understanding of biologically active molecules and their potential applications in medicine and biotechnology. Here are some intriguing aspects that capture the essence of this compound:

  • Complex Structure: The compound encompasses a wide variety of functional groups, including amine, hydroxyl, and phosphoryl groups, making it a prime candidate for activity against biological targets.
  • Biological Relevance: As a derivative of purine, its structural elements hint at potential uses in nucleoside analogs, which could mimic naturally occurring biologically significant molecules like nucleotides.
  • Potential Therapeutic Applications: Due to its multifaceted structure, this compound could be explored for therapeutic roles in diseases influenced by cellular signaling pathways, potentially including cancer treatments.
  • Inhibition Mechanism Insights: Studies suggest that compounds with similar structures can act as inhibitors of certain enzymes or as modulators of signaling pathways, which paves the way for further research.
  • Massive Library of Derivatives: The unique structural components of this phosphate derivative can inspire a wide range of modifications to enhance its efficacy and selectivity, encouraging an ever-expanding library of potential analogs.

Overall, the complexity and potential of this compound invite many questions and explorations within the realm of medicinal chemistry, encouraging cutting-edge research that could lead to breakthrough innovations in therapeutic treatments. As we continue to decipher the myriad functions of such compounds, chemistry will undoubtedly unveil further secrets that lie in their intricate molecular architectures.