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Didesethyl Chloroquine

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Identification
Molecular formula
C22H30Cl2N2O
CAS number
112205-01-1
IUPAC name
2-(6-chloro-1-oxo-3,4-dihydro-2H-carbazol-9-yl)ethyl-diethyl-ammonium;chloride
State
State

At room temperature, Didesethyl Chloroquine is typically found in a solid state as a crystalline powder.

Melting point (Celsius)
181.00
Melting point (Kelvin)
454.15
Boiling point (Celsius)
266.80
Boiling point (Kelvin)
539.95
General information
Molecular weight
392.30g/mol
Molar mass
392.3000g/mol
Density
1.3000g/cm3
Appearence

The compound appears as a white to off-white crystalline powder. It is typically odorless.

Comment on solubility

Solubility of 2-(6-chloro-1-oxo-3,4-dihydro-2H-carbazol-9-yl)ethyl-diethyl-ammonium;chloride

The solubility of 2-(6-chloro-1-oxo-3,4-dihydro-2H-carbazol-9-yl)ethyl-diethyl-ammonium;chloride can be analyzed from various perspectives due to its unique chemical structure. This compound contains both an ammonium group and a chloride ion, which influences its solubility behavior in different solvents.

Key Factors Influencing Solubility:

  • Polarity: The presence of the polar ammonium group typically enhances solubility in polar solvents like water.
  • Hydrogen Bonding: The capability of the compound to form hydrogen bonds may augment solubility in aqueous solutions.
  • Ionization: As a quaternary ammonium salt, it is expected to be fully ionized in solution, which generally increases solubility in water.
  • Temperature: Solubility may also increase with temperature, as is common with many ionic compounds.

Many sources suggest that compounds of this nature tend to be soluble in water, yet, it's essential to conduct experimental validation to ascertain the degree of solubility. Furthermore, the effects of factors such as pH, ionic strength, and presence of other solutes can significantly affect solubility.

In conclusion, while 2-(6-chloro-1-oxo-3,4-dihydro-2H-carbazol-9-yl)ethyl-diethyl-ammonium;chloride is anticipated to have favorable solubility characteristics in polar solvents, empirical studies are recommended for definitive insights.

Interesting facts

Interesting Facts about 2-(6-chloro-1-oxo-3,4-dihydro-2H-carbazol-9-yl)ethyl-diethyl-ammonium chloride

The compound 2-(6-chloro-1-oxo-3,4-dihydro-2H-carbazol-9-yl)ethyl-diethyl-ammonium chloride represents a fascinating intersection of organic chemistry and medicinal chemistry. Here are some insightful facts to explore:

  • Structural Complexity: This compound features a unique structure that combines a carbazole moiety with a diethylammonium side chain. The presence of the chlorinated and carbonyl functionalities enhances its chemical reactivity and potential biological activity.
  • Biological Relevance: Carbazole derivatives are known for their diverse range of biological activities, including anti-inflammatory, antimicrobial, and anticancer properties. This compound could be a valuable candidate for further pharmacological studies.
  • Ion Exchange Properties: The diethylammonium chloride component adds ionic characteristics that may result in interesting interactions with biological membranes, potentially influencing drug delivery and absorption.
  • Research Potential: The unique structure and functional groups provide a broad scope for exploring new synthetic pathways and biological activity. As such, it stands as an intriguing target for medicinal chemists aiming to develop novel therapeutics.
  • Synthetic Application: Compounds with such structural complexity often serve as precursors in organic synthesis, allowing for the creation of novel chemical entities with tailored properties.

In the words of a prominent chemist, “The beauty of chemistry lies in its ability to create endless possibilities.” This compound embodies that sentiment, illustrating how modifications to a core structure can yield benefits not only in synthetic chemistry but also in medical applications. As research continues, we may uncover even more exciting potential locked within the molecular architecture of this compound.

Synonyms
Of 2451
18638-87-4
Carbazol-1(2H)-one, 3,4-dihydro-6-chloro-9-(2-(diethylamino)ethyl)-, monohydrochloride
9-(2-(Diethylamino)ethyl)-6-chloro-2,3,4,9-tetrahydro-1H-carbazol-1-one monohydrochloride