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2-(6-chloro-1,4-dioxaspiro[4.5]decan-3-yl)piperidine

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Identification
Molecular formula
C13H22ClNO2
CAS number
60643-86-9
IUPAC name
2-(6-chloro-1,4-dioxaspiro[4.5]decan-3-yl)piperidine
State
State

At room temperature, 2-(6-chloro-1,4-dioxaspiro[4.5]decan-3-yl)piperidine is generally a solid. It is handled and stored in a dry, typically opaque container to protect from moisture and light which can affect its stability.

Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
354.00
Boiling point (Kelvin)
627.15
General information
Molecular weight
243.77g/mol
Molar mass
243.7350g/mol
Density
1.2800g/cm3
Appearence

The compound is typically a crystalline solid and may appear as a white to off-white powder. Its crystalline structure and powder form are common for many organic pharmaceutical compounds. Specific details on its precise crystal form or powder characteristics were not provided in the available data.

Comment on solubility

Solubility of 2-(6-chloro-1,4-dioxaspiro[4.5]decan-3-yl)piperidine

The solubility of 2-(6-chloro-1,4-dioxaspiro[4.5]decan-3-yl)piperidine can be influenced by several factors. This compound possesses structural characteristics that suggest a unique solubility profile. Here are some key points to consider:

  • Polar Functional Groups: The presence of the dioxaspiro and piperidine components may impart polarity to the molecule, enhancing its solubility in polar solvents such as water and ethanol.
  • Hydrogen Bonding: The potential for hydrogen bonding due to the hydroxyl groups of the dioxaspiro structure can also contribute to increased solubility in aqueous solutions.
  • Basicity of Piperidine: The piperidine ring may act as a weak base, which can further affect the solubility in different pH environments.
  • Alkyl Chain Effects: The bulky spiro structure may hinder solubility in non-polar solvents, indicating a preference for solubility in moderately polar solvents.

As a general observation, the solubility of this compound might be characterized as follows:

  • Water: Moderate to high solubility due to polar functional groups.
  • Organic Solvents: Varies significantly; may exhibit low solubility in non-polar solvents.

In conclusion, while definite solubility data for this specific compound may need further experimental verification, the structural analysis provides a strong basis for predicting its solubility characteristics. Therefore, researchers should undertake solubility studies under controlled conditions to gain a better understanding of its behavior in various solvents.

Interesting facts

Interesting Facts about 2-(6-chloro-1,4-dioxaspiro[4.5]decan-3-yl)piperidine

2-(6-chloro-1,4-dioxaspiro[4.5]decan-3-yl)piperidine is a fascinating compound that stands out due to its unique structure and potential applications in various fields of science. Here are some intriguing points about this compound:

  • Unique Structure: This compound features a spirocyclic architecture, which is a characteristic that can influence its chemical behavior and biological activity. The presence of both piperidine and dioxaspiro groups adds complexity to its structure.
  • Pharmaceutical Potential: Compounds similar to 2-(6-chloro-1,4-dioxaspiro[4.5]decan-3-yl)piperidine have been investigated for their potential therapeutic benefits, particularly in the realm of neuropharmacology. They may affect neurotransmitter systems and could lead to the development of new medications.
  • Chlorine Atom Influence: The inclusion of a chlorine atom in the structure can significantly impact the compound's reactivity, stability, and solubility. Chlorinated compounds often exhibit enhanced biological properties.
  • Research Applications: This compound may serve as a valuable tool in organic synthesis or as a precursor in the development of more complex molecules, showcasing its versatility in synthetic chemistry.
  • Interdisciplinary Appeal: Chemists, pharmacologists, and materials scientists alike find interest in this compound as it bridges multiple scientific disciplines, enabling collaboration and innovation.

Overall, 2-(6-chloro-1,4-dioxaspiro[4.5]decan-3-yl)piperidine represents a compelling subject of research, with its unique blend of structural features making it a candidate for further exploration in both chemical and medicinal chemistry.