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Clomipramine hydrochloride

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Identification
Molecular formula
C19H24ClN3
CAS number
17321-77-6
IUPAC name
[2-(6-chloro-1H-indol-3-yl)-1-methyl-ethyl]ammonium;chloride
State
State

Clomipramine hydrochloride exists as a solid at room temperature.

Melting point (Celsius)
193.00
Melting point (Kelvin)
466.15
Boiling point (Celsius)
270.00
Boiling point (Kelvin)
543.15
General information
Molecular weight
351.30g/mol
Molar mass
314.2070g/mol
Density
1.5000g/cm3
Appearence

Clomipramine hydrochloride generally appears as a white or off-white crystalline powder.

Comment on solubility

Solubility of [2-(6-chloro-1H-indol-3-yl)-1-methyl-ethyl]ammonium;chloride

The solubility of the compound [2-(6-chloro-1H-indol-3-yl)-1-methyl-ethyl]ammonium chloride can be categorized based on certain factors that influence its behavior in various solvents. Here are some key observations:

  • Solvent Dependence: This compound is likely to be well-soluble in polar solvents, such as water, due to the presence of the ionic ammonium (NH4+) and chloride (Cl-) groups.
  • Hydrophobic Interactions: The presence of the indole moiety suggests that it may have some hydrophobic characteristics, which could affect its solubility in non-polar solvents.
  • Temperature Influence: Like many ionic compounds, solubility may increase with temperature, making it more favorable to dissolve in warm solvents.

In conclusion, while [2-(6-chloro-1H-indol-3-yl)-1-methyl-ethyl]ammonium chloride is expected to exhibit significant solubility in polar media, the precise solubility will depend on specific conditions including solvent choice, temperature, and concentration. Understanding these factors can provide valuable insights into the compound's applications in various fields.

Interesting facts

Interesting Facts about [2-(6-chloro-1H-indol-3-yl)-1-methyl-ethyl]ammonium;chloride

This intriguing compound is a member of the ammonium salts family and is known for its complex structure and noteworthy properties. Here are some compelling points to consider:

  • Biological Significance: The indole ring system is fundamental in many biological processes, playing a critical role as a building block for numerous natural substances, including essential amino acids, hormones, and neurotransmitters.
  • Pharmacological Potential: The presence of a chloro-substituent on the indole ring can enhance the compound's biological activity. There is ongoing research into its possible applications in medicinal chemistry, particularly concerning anti-cancer and anti-inflammatory properties.
  • Structure-Activity Relationship: The configuration of substituents around the indole core influences the compound's reactivity and efficacy. Such studies could open doors for the development of novel therapeutic agents.
  • Ion Exchange Properties: As an ammonium salt, the compound can participate in ion exchange reactions, which could make it useful in various applications including drug delivery systems and as a biochemical probe.
  • Environmental Impact: Understanding the behavior of this salt in the environment is crucial. Its stability, reactivity, and potential toxicity need to be evaluated for safe application in pharmaceutical formulations.

In summary, [2-(6-chloro-1H-indol-3-yl)-1-methyl-ethyl]ammonium;chloride is not just a compound with interesting structural features; it also holds significant promise in various scientific fields. As research evolves, the insights gained from studying this compound could pave the way for new discoveries in pharmacology and natural product chemistry.

Synonyms
3-(2-Aminopropyl)-6-chloroindole hydrochloride
1204-05-3
INDOLE, 3-(2-AMINOPROPYL)-6-CHLORO-, HYDROCHLORIDE