Quetiapine fumarate | Solubility of Things

Identification

Molecular formula

C₂₁H₂₅ClN₂O₂

CAS number

111974-72-2

IUPAC name

2-(6-ethyl-1,4-dioxaspiro[4.5]decan-3-yl)piperidin-1-ium;chloride

State

At room temperature, this compound is in a solid state.

Melting point (Celsius)

173.00

Melting point (Kelvin)

446.00

Boiling point (Celsius)

742.00

Boiling point (Kelvin)

1 015.00

General information

Molecular weight

383.90g/mol

Molar mass

383.4470g/mol

Density

1.2000g/cm³

Appearence

This compound appears as a white or almost white crystalline powder. It is typically odorless or has a faint odorous smell and has a bitter taste.

Comment on solubility

Solubility of 2-(6-ethyl-1,4-dioxaspiro[4.5]decan-3-yl)piperidin-1-ium;chloride

The solubility of the compound 2-(6-ethyl-1,4-dioxaspiro[4.5]decan-3-yl)piperidin-1-ium;chloride can be quite intriguing due to its unique structure. Here are several key points to consider regarding its solubility characteristics:

Polarity: The presence of the piperidin-1-ium cation suggests that the compound is likely to be more polar.
Chloride Ion: The inclusion of the chloride counter-ion may increase the overall solubility in polar solvents, especially in water.
Hydrogen Bonding: The dioxaspiro unit could facilitate hydrogen bonding with solvents, enhancing solubility in certain conditions.
Solvent Compatibility: This compound might exhibit increased solubility in solvents such as methanol or ethanol, owing to their polar nature.

In summary, it is anticipated that 2-(6-ethyl-1,4-dioxaspiro[4.5]decan-3-yl)piperidin-1-ium;chloride would be soluble in polar solvents, with its solubility being influenced by factors like temperature, pH, and the specific nature of the solvent used. Understanding these solubility parameters can facilitate its practical applications in various chemical processes.

Interesting facts

Interesting Facts about 2-(6-ethyl-1,4-dioxaspiro[4.5]decan-3-yl)piperidin-1-ium;chloride

This fascinating compound, known as 2-(6-ethyl-1,4-dioxaspiro[4.5]decan-3-yl)piperidin-1-ium;chloride, presents an intriguing combination of structural complexity and potential applications. Here are some noteworthy aspects:

Structural Uniqueness: The compound features a spirocyclic structure, which is characterized by two or more rings that share a single atom. This structural arrangement is particularly interesting for its implications in medicinal chemistry as spiro compounds often exhibit *unique biological activities*.
Potential Pharmacological Applications: Compounds like this one, with heterocyclic elements (the piperidine ring), are frequently explored in the pharmaceutical field for their *potential as drug candidates*. Research on piperidine derivatives has shown promise in treating various conditions, including neurological disorders.
Ion Exchange Capability: The presence of the chloride ion suggests that the compound may play a role in *ionic interactions*, which are crucial in biological systems. This can influence permeability and solubility, affecting how the compound behaves in different environments.
Research Opportunities: Given its complex structure, this compound opens avenues for further *synthetic research*. Chemists may explore modifications to enhance its efficacy or discover new derivatives with improved properties.
Interdisciplinary Applications: Beyond pharmaceuticals, the unique properties of this compound could make it valuable in materials science, especially in designing new polymers or ligands in coordination chemistry.

In summary, 2-(6-ethyl-1,4-dioxaspiro[4.5]decan-3-yl)piperidin-1-ium;chloride represents a bridge between *theoretical chemistry and practical applications*, making it a subject of interest for both researchers and students alike. Its *structural intricacies* and potential uses illustrate the exciting possibilities within the realm of chemical compounds.

Synonyms

beta-6-Ethyl-2-(2-piperidyl)-1,4-dioxaspiro(4.5)decane hydrochloride

1,4-DIOXASPIRO(4.5)DECANE, 6-ETHYL-2-(2-PIPERIDYL)-, HYDROCHLORIDE, beta-

7538-28-5