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Naproxol

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Identification
Molecular formula
C14H16O2
CAS number
568-65-2
IUPAC name
2-(6-methoxy-2-naphthyl)propan-1-ol
State
State

At room temperature, naproxol is a solid.

Melting point (Celsius)
98.00
Melting point (Kelvin)
371.20
Boiling point (Celsius)
374.20
Boiling point (Kelvin)
647.40
General information
Molecular weight
218.28g/mol
Molar mass
218.2760g/mol
Density
1.0434g/cm3
Appearence

Naproxol typically appears as a white to off-white crystalline powder. It is solid at room temperature and is known for its characteristic crystalline texture.

Comment on solubility

Solubility of 2-(6-methoxy-2-naphthyl)propan-1-ol

The compound 2-(6-methoxy-2-naphthyl)propan-1-ol exhibits interesting solubility characteristics due to its hybrid structure. The presence of the naphthalene ring contributes to its hydrophobicity, while the alcohol functional group introduces a degree of hydrophilicity, which can influence its solubility in various solvents. Key points regarding its solubility include:

  • Soluble in Organic Solvents: This compound is likely to be soluble in non-polar organic solvents such as ethanol, methanol, and dichloromethane due to the presence of the hydrophobic naphthalene moiety.
  • Limited Water Solubility: Given its naphthyl structure, its solubility in water may be limited, as the large hydrocarbon component does not favor interaction with water molecules.
  • Temperature Dependence: Like many organic compounds, solubility may vary with temperature; increasing temperature often enhances solubility in organic solvents.
  • Alcohol Compatibility: Since it contains an alcohol functional group, it may demonstrate higher solubility in alcohol solutions, particularly in polar solvents.

In summary, while 2-(6-methoxy-2-naphthyl)propan-1-ol may find good solubility in various organic solvents, its overall solubility profile reveals a balance between hydrophilic and hydrophobic interactions, underscoring the complex nature of its chemical behavior.

Interesting facts

Interesting Facts about 2-(6-methoxy-2-naphthyl)propan-1-ol

2-(6-methoxy-2-naphthyl)propan-1-ol is a fascinating compound that has garnered attention in various fields, including organic chemistry and medicinal chemistry. It showcases the intricate relationship between molecular structure and function.

Key Features:

  • Structure and Function: This compound features a naphthalene moiety, which contributes to its hydrophobic character and can influence its interaction with biological systems.
  • Biological Relevance: Certain derivatives of naphthalene have been explored for their potential pharmacological properties, including anti-inflammatory and analgesic effects, making this compound of interest in drug development.
  • Synthetic Pathways: The synthesis of this compound can involve various organic reactions, including Grignard reactions or reduction processes, showcasing the versatility and creativity of synthetic organic chemistry.

Moreover, the presence of the methoxy group enhances the compound's electronic properties, potentially affecting its reactivity and interaction with other molecules. As a member of the class of alcohols, it serves as a functional group that can participate in numerous chemical reactions, including esterifications and oxidations.

In summary, 2-(6-methoxy-2-naphthyl)propan-1-ol is more than just a simple organic compound; it embodies the complexities of chemical interactions and the vast potential for discovery in organic and medicinal chemistry. As noted by chemists, “The structures that we create today can lead to the medicines of tomorrow.”

Synonyms
2-(6-methoxynaphthalen-2-yl)propan-1-ol
NCGC00095068-01
SCHEMBL8471214
CHEMBL4078616
SCHEMBL29979997
DTXSID50860358
LTRANDSQVZFZDG-UHFFFAOYSA-N
2-(6-methoxy-2-naphthyl)propanol
BBA15936
2-(6-methoxy-2-naphthyl)-l-propanol
AKOS005360817
2-(6-methoxy-2-naphthyl)propan-1-ol
2-(6-methoxy-2-naphthyl)-propan-1-ol
NCGC00095068-02
NS00123306